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Ameloblastic Fibroma

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What are the clinical features of ameloblastic fibroma?   Ameloblastic fibroma is an asymptomatic benign neoplasm with epithelium and mesenchyme proliferation. The lesion can be seen radiographically, move adjacent teeth and expand the cortex.  
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What are the demographic features of ameloblastic fibroma?   Ameloblatic fibroma is a rare lesion, it does have a slight male predilection and occurs in young patients, the first two decades. The most common location is posterior mandible (70%) and pericoronal to an unerupted tooth (75%).  
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How would you describe an ameloblastic fibroma lesion?   Ameloblastic fibroma is a benign neoplasm. Radiographically, it appears as a well demarcated, unilocular (mostly) radiolucency with a thin sclerotic rim. It can expand the cortex and move adjacent teeth. There are NO calcifications within the lesion.  
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What are the histologic features of ameloblastic fibroma (AF)?   AF contains primitive mesenchymal tissue and immature stroma. Fibrous portion: large, stellate, spindled nuclei with mild-moderate cellularity. Epithelial portion: double-layered strands of cuboidal odontogenic epithelium and ameloblastoma-like islands.  
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What would you include in the differential diagnosis for ameloblastic fibroma?   The differential diagnoses for ameloblastic fibroma include: dentigerous cyst, odontogenic keratocyst, and orthokeratinized odontogenic cyst.  
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What is the treatment for ameloblastic fibroma?   The treatment for amelobalstic fibroma is surgical removal or curettage. With curettage treatment only, there is a 40% risk of recurrence.  
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Created by: emma.carpenter
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