Lip Pits
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| Lip Pits Definition | Lip pits are invaginations observed in the lip mucosa.
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| Commissural Lip Pits | Clinical features of commissural lip pits include small mucosal invaginations bilaterally at the corners of the mouth on the vermillion border. This can also occur unilaterally. Depth of invagination ranges from 1-4mm.
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| Paramedian Lip Pits | Rare congenital invaginations of the lower lip. Found bilaterally with symmetric fistulas on either side of the midline of the vermillion border of the lower lip. Much deeper than commissural, 1.5cm depth. Autosomal dominant inheritance.
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| Alternate Names for Lip Pits | Lip depression, lip sinus, midline sinus of the upper lip, congenital sinus of the lower lip.
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| Lip Pits Demographics | Commissural lip pits occur in 12-20% of the adult population. Infrequently found in children. Van der Woude syndrome is about 1:75,000-1:100,000 births.
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| Lip Pits Differential Diagnoses | Rule out syndromes such as Van der Woude, Popliteal Pterygium Syndrome, and Kabuki Syndrome, especially important when the patient presents with CL +/- CP.
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| Treatment for Commissural Lip Pits | No treatment recommended for commissural lip pits. Surgical excision will be necessary in extremely rare instances where salivary excretions may be excessive or presence of secondary infection.
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| Treatment for Paramedian Lip Pits | Surgical excision for cosmetic reasons.
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| Microscopic Features of Lip Pits | A layer of squamous epithelium lines a blind pouch, and the lumen will beb filled with desquamated epithelial cells.
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djain414
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