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Duke PA micro

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Question
Answer
What type of cell walls do mycobacteria have?   waxy cell walls  
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What type of cell walls do mycoplasma have?   no cell walls  
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beta lactams   group of antibiotics that are directed toward gram positive bacteria  
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How do beta lactams work?   inhibit cross-linking of peptidoglycan  
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What are the most common cell wall inhibitors?   beta-lactams  
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What are examples of beta lactams?   penicillins, cephalosporins, carbapenems, monobactams  
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Where do beta lactams get their name?   they share a common beta lactam ring as their basic structural unit  
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What are other cell wall inhibitors?   vancomycin, bacitracin, many of the anti-tuberculosis agents  
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How do cell membrane agents work?   disrupt either cytoplasmic membrane of Gram - outer membrane  
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How do ribosome agents work?   disrupts protein synthesis at both 30S and 50S ribosomes  
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What are the two remaining antibacterial "targets" of action?   antimetabolism and inhibition of DNA or RNA synthesis  
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How do antimetabolism agents work?   mimic the structure of a required metabolite  
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What is an example of an antimetabolism agent?   Septra  
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What is an example of a DNA or RNA synthesis agent?   Cipro  
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What are the two ways antibiotics affect bacteria?   bactericidal or bacteriostatic  
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Bactericidal   killing  
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bacteriostatic   inhibiting growth  
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Inhibit cell wall synthesis, nucleic acid synthesis and alter cell membrane permeability   bactericidal  
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inhibit protein synthesis are usually…   bactericidal  
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folic acid inhibitors   bactericidal  
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Created by: ges13
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