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Bacteriology 2
Duke PA micro
| Question | Answer |
|---|---|
| What type of cell walls do mycobacteria have? | waxy cell walls |
| What type of cell walls do mycoplasma have? | no cell walls |
| beta lactams | group of antibiotics that are directed toward gram positive bacteria |
| How do beta lactams work? | inhibit cross-linking of peptidoglycan |
| What are the most common cell wall inhibitors? | beta-lactams |
| What are examples of beta lactams? | penicillins, cephalosporins, carbapenems, monobactams |
| Where do beta lactams get their name? | they share a common beta lactam ring as their basic structural unit |
| What are other cell wall inhibitors? | vancomycin, bacitracin, many of the anti-tuberculosis agents |
| How do cell membrane agents work? | disrupt either cytoplasmic membrane of Gram - outer membrane |
| How do ribosome agents work? | disrupts protein synthesis at both 30S and 50S ribosomes |
| What are the two remaining antibacterial "targets" of action? | antimetabolism and inhibition of DNA or RNA synthesis |
| How do antimetabolism agents work? | mimic the structure of a required metabolite |
| What is an example of an antimetabolism agent? | Septra |
| What is an example of a DNA or RNA synthesis agent? | Cipro |
| What are the two ways antibiotics affect bacteria? | bactericidal or bacteriostatic |
| Bactericidal | killing |
| bacteriostatic | inhibiting growth |
| Inhibit cell wall synthesis, nucleic acid synthesis and alter cell membrane permeability | bactericidal |
| inhibit protein synthesis are usually… | bactericidal |
| folic acid inhibitors | bactericidal |
Created by:
ges13
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