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Advanced Biology 16

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Term
Definition
Bacteriaphages   A virus that infects bacteria.  
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Transformation   A change in genotype and phenotype due to the assimilation of external DNA by a cell.  
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Virus   An infectious particle incapable of replicating outside of a cell, consisting of an RNA or DNA genome surrounded by a protein coat (capsid).  
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Double-Helix   The form of native DNA, referring to its two adjacent antiparallel polynucleotide strands wound around an imaginary axis into a spiral shape.  
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Origin of Replication   Site where the replication of a DNA molecule begins, consisting of a specific sequence of nucleotides.  
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Replication Fork   A Y-shaped region on a replicating DNA molecule where the parental strands are being unwound and new strands are being synthesized.  
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Primer   A short stretch of RNA with a free 3′ end, bound by complementary base pairing to the template strand and elongated with DNA nucleotides during DNA replication.  
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DNA Polymerase   An enzyme that catalyzes the elongation of new DNA (for example, at a replication fork) by the addition of nucleotides to the 3′ end of an existing chain.  
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Leading Strand   The new complementary DNA strand synthesized continuously along the template strand toward the replication fork in the mandatory 5′ - 3′ direction.  
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Lagging Strand   A discontinuously synthesized DNA strand that elongates by means of Okazaki fragments, each synthesized in a 5′ - 3′ direction away from the replication fork.  
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Nuclease   An enzyme that cuts DNA or RNA, either removing one or a few bases or hydrolyzing the DNA or RNA completely into its component nucleotides.  
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Telomeres   The tandemly repetitive DNA at the end of a eukaryotic chromosome’s DNA molecule.  
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Chromatin   The complex of DNA and proteins that makes up eukaryotic chromosomes.  
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Created by: Mr.Devine
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