Immunoheme Lab Exam
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
|
|
||||
|---|---|---|---|---|---|
| A | A antigen, anti-B antibody
🗑
|
||||
| B | B antigen, anti-A antibody
🗑
|
||||
| O | no antigen, anti-A and anti-B antibody
🗑
|
||||
| AB | A and B antigen, no antibodies
🗑
|
||||
| somatic cells are diploid or haploid | diploid
🗑
|
||||
| the most common blood group antigens are of what chemical composition | glycoproteins/lipids
🗑
|
||||
| Name the 2 immunoglobulin classes that comprise most blood group antibodies | IgM and IgG
🗑
|
||||
| Expose you and determine your blood type | histoantigens
🗑
|
||||
| No H antigen (hh genotype) | bombay
🗑
|
||||
| type 1 linkage | beta 1-3 linkage; secretions, H substance
🗑
|
||||
| Type 2 linkage | beta 1-4 linkage; RBC antigens
🗑
|
||||
| H+H = | O
🗑
|
||||
| H+A= | A
🗑
|
||||
| H+B | B
🗑
|
||||
| H+A+B= | AB
🗑
|
||||
| what term is defined as the basic unit of inheritance | gene
🗑
|
||||
| Genetic makeup of a trait | genotype
🗑
|
||||
| physical expression of a trait | phenotype
🗑
|
||||
| Why is the ABO blood group the most clinically significant | acute hemolytic transfusion reactions
🗑
|
||||
| Universal blood donor | O
🗑
|
||||
| Universal blood receiver | AB
🗑
|
||||
| Universal plasma donor | AB
🗑
|
||||
| Universal plasma recipient | O
🗑
|
||||
| Looking for antibody? | React with patient cells
🗑
|
||||
| Looking for antigen? | React with anti-serum
🗑
|
||||
| Forward typing determines.... | antigen
🗑
|
||||
| Reverse typing determines.. | antibodies
🗑
|
||||
| What does LISS do? | enhancement tool, negates negative charge on RBCs so they can stack together
🗑
|
||||
| Which FUT gene goes with H antigen enzyme | FUT1
🗑
|
||||
| Which FUT gene goes with secretor enzyme | FUT2
🗑
|
||||
| Which FUT gene goes with lewis enzyme | FUT3
🗑
|
||||
| 80% of the population has this gene | secretor gene
🗑
|
||||
| bind better and bind complement | IgM
🗑
|
||||
| Larger | IgM
🗑
|
||||
| Room temperature or less (won't cause physical harm during cross over because it won't react) | IgM
🗑
|
||||
| Direct agglutination | IgM
🗑
|
||||
| Smaller | IgG
🗑
|
||||
| Can cross the placenta and cause hemolytic disease of the newborn | IgG
🗑
|
||||
| Indirect agglutination | IgG
🗑
|
||||
| Worse for cross-over | IgG
🗑
|
||||
| Genes make antigens in what two ways? | Directly and enzymatically
🗑
|
||||
| what is the most common blood group in caucasian americans | O+
🗑
|
||||
| what is the least common blood group in general | AB-
🗑
|
||||
| what is the bombay genotype | hh
🗑
|
||||
| why can bombay people only receive bombay blood? | they have anti-h group and all other groups have H antigen
🗑
|
||||
| what enzyme codes the A gene; sugar transferred | nacetylgalactosaminyltransferase; nacetylgalactosamine
🗑
|
||||
| what enzyme codes the B gene; sugar transferred | galactosyltransferase; galactose
🗑
|
||||
| what enzyme codes the H gene; sugar transferred |
🗑
|
||||
| what does DAT stand for? | direct antibody testing
🗑
|
||||
| what does IAT stand for? | indirect antibody testing
🗑
|
||||
| where is the antibody located when you're testing DAT? | cells
🗑
|
||||
| where is the antibody located when testing IAT? | plasma
🗑
|
||||
| What does DAT also go by? | Direct coombs test
🗑
|
||||
| what does IAT also go by? | antibody screen
🗑
|
||||
| antibody to lewis | Le a- b- ; IgM
🗑
|
||||
| Additive to extend storage life of RBC's and whole blood | CPDA-1
🗑
|
||||
| how do platelets need to be stored | @ room temperature in an agitator (keeps them mixed so they don't stick together and the pH stable)
🗑
|
||||
| is the lewis system technically a blood group? | no, antigen isn't manufactured by RBCs. Done by tissues and dumped into the plasma where RBC's adsorb it
🗑
|
||||
| two FUT genes = two fucose = | Leb
🗑
|
||||
| parabombay has ABH antigens in what but not in what? | secretions, RBCs
🗑
|
||||
| bombay phenotype has no ABH antigens | in secretions or on cells
🗑
|
||||
| what is AHG | Anti-human globulin
🗑
|
||||
| what genetic theory is the most recent and accepted as correct? | tippett
🗑
|
||||
| Anti-D gives you problems with... | future transfusions and pregnancies
🗑
|
||||
| Which genetic theory has no little d and has antithetical alleles (you get one or the other) | Fisher-Race
🗑
|
||||
| Numbers assigned to letters and their assigned positive or negative | Rosenfield terminology
🗑
|
||||
| What causes 1. increased osmotic fragility 2. mild hemolytic anemia 3. stomatocytes | Rh null
🗑
|
||||
| what is the volume of a typical unit of whole blood | 450 ml +- 45 ml
🗑
|
||||
| 4 components of whole blood donation | RBCs, AHF, fresh frozen plasma, platelets
🗑
|
||||
| what is the purpose of citrate? | anticoagulant
🗑
|
||||
| what is the purpose of phosphate? | buffers solution
🗑
|
||||
| what is the purpose of dextrose | energy
🗑
|
||||
| what is the purpose of adenine | increases survival (preservative)
🗑
|
||||
| 3 important elements for platelet storage | temperature (rm. temp), gentle agitation, storage duration (5 days)
🗑
|
||||
| what is the gene product for the se gene | alpha 1,2 fucoslytransferase
🗑
|
Review the information in the table. When you are ready to quiz yourself you can hide individual columns or the entire table. Then you can click on the empty cells to reveal the answer. Try to recall what will be displayed before clicking the empty cell.
To hide a column, click on the column name.
To hide the entire table, click on the "Hide All" button.
You may also shuffle the rows of the table by clicking on the "Shuffle" button.
Or sort by any of the columns using the down arrow next to any column heading.
If you know all the data on any row, you can temporarily remove it by tapping the trash can to the right of the row.
To hide a column, click on the column name.
To hide the entire table, click on the "Hide All" button.
You may also shuffle the rows of the table by clicking on the "Shuffle" button.
Or sort by any of the columns using the down arrow next to any column heading.
If you know all the data on any row, you can temporarily remove it by tapping the trash can to the right of the row.
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
Created by:
10209767480851378
Popular Biology sets