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Blood and CSF Unit

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Question
Answer
How is Streptobacillus moniliformis and Spirillum minor similar in their mode of infection?   Infect humans through "rodent bites"  
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What is the difference in gram stain between Streptobacillus moniliformis and Spirillum minor?   Streptobacillus is a gram negative rod (Sometimes coccobacilluary or coccoid forms with extreme polymorphism) Spirillum minor is a gram negative spirochete  
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How is Spirillum minor diagnosed?   Diagnosis dependent on demonstrating organisms in clinical specimens.  
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What are the three stages of a Borrelia burgdorferi infection?   Stage 1 - lesions/bulls eye skin lesion Stage 2 - Dissemination of the spirochete - may manifest arthritis, neurologic disorders, and carditis Stage 3 - Chronic Phase - arthritis is the hallmark  
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How is Buorrelia burgdorferi cultured?   Kelly's Medium, 33 Celsius, 1 month  
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How is Leptospira interrogans cultured?   Fletcher or Stuart's Media, 30 Celsius, 6-14 days up to 6 weeks  
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What are the three genus of spirochetes that are clinically relevant?   1) Borrelia 2) Leptospira 3) Treponema  
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