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Spirochetes
Blood and CSF Unit
Question | Answer |
---|---|
How is Streptobacillus moniliformis and Spirillum minor similar in their mode of infection? | Infect humans through "rodent bites" |
What is the difference in gram stain between Streptobacillus moniliformis and Spirillum minor? | Streptobacillus is a gram negative rod (Sometimes coccobacilluary or coccoid forms with extreme polymorphism) Spirillum minor is a gram negative spirochete |
How is Spirillum minor diagnosed? | Diagnosis dependent on demonstrating organisms in clinical specimens. |
What are the three stages of a Borrelia burgdorferi infection? | Stage 1 - lesions/bulls eye skin lesion Stage 2 - Dissemination of the spirochete - may manifest arthritis, neurologic disorders, and carditis Stage 3 - Chronic Phase - arthritis is the hallmark |
How is Buorrelia burgdorferi cultured? | Kelly's Medium, 33 Celsius, 1 month |
How is Leptospira interrogans cultured? | Fletcher or Stuart's Media, 30 Celsius, 6-14 days up to 6 weeks |
What are the three genus of spirochetes that are clinically relevant? | 1) Borrelia 2) Leptospira 3) Treponema |