ondansetron, diltiazem, glucagon, nalmefene, vasopressin
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| Vasopressin GENERIC NAME | Vasopressin
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| Vasopressin BRAND NAME | Pitressin synthetic
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| Vasopressin CLASS | Antidiuretic hormone
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| Vasopressin MECHANISM OF ACTION | Stimulation of V1 smooth muscle receptors, potent vasoconstrictor when given in high doses.
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| Vasopressin INDICATIONS | Alternate vasopressor to the first or second dose of epinephrine in cardiac arrest, may be useful in cases of vasodilatory shock
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| Vasopressin CONTRAINDICATIONS | Responsive patients with cardiac disease.
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| Vasopressin ADVERSE REACTIONS | Bronchoconstriction, ischemic chest pain, N/V.
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| Vasopressin INCOMPATABILITIES/DRUG INTERACTIONS | None
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| Vasopressin DOSE/ROUTE Adult | 40 unit one time dose IV/IO to replace the first or second dose of epinephrine in cardiac arrest.
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| Vasopressin ONSET OF ACTION | Immediate
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| Vasopressin PEAK EFFECTS | Variable
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| Vasopressin DURATION OF ACTION | Variable
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| Vasopressin AZ DRUG BOX SUPPLY RANGE | 40 units (optional)
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| DILTIAZEM GENERIC NAME | DILTIAZEM
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| DILTIAZEM BRAND NAME | Cardizem
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| DILTIAZEM CLASS | Calcium Channel Blocker, Calcium antagonist
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| DILTIAZEM MECHANISM OF ACTION | Blocks calcium form moving into the heart muscle cell, which prolongs the conduction of electrical impulses through the AV node.
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| DILTIAZEM INDICATIONS | ventricular rate control in rapid a-fib and a-flutter, and for PSVT refractory to adenosine.
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| DILTIAZEM CONTRAINDICATIONS | Hypotension , heart block, heart failure, Beta Blocker Use
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| DILTIAZEM ADVERSE REACTIONS | hypotension, Bradycardia, heart block, chest pain, and Asystole
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| DILTIAZEM INCOMPATABILITIES/DRUG INTERACTIONS | Avoid use in patients with poison- or drug-induced tachycardia. Calcium chloride can be used to prevent the Hypotensive effects of this drug and treat patients with a calcium channel blocker overdose.
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| DILTIAZEM DOSE/ROUTE Adult Dosage Initial | 0.25 mg/kg IV over 2 minutes If response is inadequate, repeat in 15 minutes 0.35 mg/kg over 2 minutes. Maintenance infusion 5.0 to 15 mg/hr
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| DILTIAZEM ONSET OF ACTION | immediately
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| DILTIAZEM PEAK EFFECTS | 2 hours
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| DILTIAZEM DURATION OF ACTION | 6 hours
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| DILTIAZEM AZ DRUG BOX SUPPLY RANGE | 25 mg
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| Glucagon GENERIC NAME | None
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| Glucagon BRAND NAME | Glucagon
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| Glucagon CLASS | Hyperglycemic agent, insulin antagonist
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| Glucagon MECHANISM OF ACTION | Converts glycogen to glucose
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| Glucagon INDICATIONS | hypoglycemia, beta blocker overdose.
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| Glucagon CONTRAINDICATIONS | Hyperglycemia, hypersensitivity
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| Glucagon ADVERSE REACTIONS | N/V tachycardia, hypertension
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| Glucagon INCOMPATABILITIES/DRUG INTERACTIONS | Incompatible in solution with most other substances.
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| Glucagon DOSE/ROUTE Adult Hypoglycemia | 1mg IM. May repeat in 7-10 minutes.
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| Glucagon DOSE/ROUTE Adult, beta blocker overdose | 5mg over 1 min. second dose of 10mg if symptoms of Bradycardia or hypotension recur.
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| Glucagon DOSE/ROUTE Pediatric, hypoglycemia | 0.5-1mg IM.
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| Glucagon ONSET OF ACTION | 1 minute
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| Glucagon PEAK EFFECTS | 30 minutes
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| Glucagon DURATION OF ACTION | Variable
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| Glucagon AZ DRUG BOX SUPPLY RANGE | 2mg.
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| NALMEFENE GENERIC NAME | NALMEFENE HCl
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| NALMEFENE BRAND NAME | Revex
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| NALMEFENE CLASS | narcotic antagonist
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| NALMEFENE MECHANISM OF ACTION | Competitive inhibition at narcotic receptor sites
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| NALMEFENE INDICATIONS | Opioid overdoses when Naloxone is not available
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| NALMEFENE CONTRAINDICATIONS | Hypersensitivity
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| NALMEFENE ADVERSE REACTIONS | Withdrawal symptoms, N/V, diaphoresis, increased heart rate, v-fib, hypotension or hypertension.
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| NALMEFENE INCOMPATABILITIES/DRUG INTERACTIONS | Should not be mixed with other drugs
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| NALMEFENE DOSE/ROUTE Adult Dosage | IV, IM, and SC
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| NALMEFENE ONSET OF ACTION | 2 minutes
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| NALMEFENE PEAK EFFECTS | Variable
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| NALMEFENE DURATION OF ACTION | 8 hours
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| NALMEFENE AZ DRUG BOX SUPPLY RANGE | 4mg optional
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| Ondansetron GENERIC NAME | Ondansetron
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| Ondansetron BRAND NAME | Zofran
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| Ondansetron CLASS | Antiemetic agent
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| Ondansetron MECHANISM OF ACTION | Selectively blocks serotonin 5-HT3 receptors located in the CNS .
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| Ondansetron INDICATIONS | N/V
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| Ondansetron CONTRAINDICATIONS | Hypersensitivity,Use with caution in patients with hepatic impairment
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| Ondansetron ADVERSE REACTIONS | Headache, dizziness, sedation, Chest pain, arrhythmias
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| Ondansetron INCOMPATABILITIES/DRUG INTERACTIONS | Inducers or inhibitors of P450 drug metabolizing enzymes may alter the clearance of Ondansetron.
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| Ondansetron DOSE/ROUTE Adult Dosage | 4 – 8 mg IV slow push over 2 – 5 minutes
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| Ondansetron DOSE/ROUTE Pediatric Dosage | 0.1 mg/kg IV slow push over 2 – 5 minutes max dose 4mg
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| Ondansetron ONSET OF ACTION | 30 minutes
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| Ondansetron PEAK EFFECTS | unknown
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| Ondansetron DURATION OF ACTION | unknown
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| Ondansetron AZ DRUG BOX SUPPLY RANGE | 8mg
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Created by:
klindley
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