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micro final

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Question
Answer
sterilization   no life form present  
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microbicidal   kills microbes  
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bactericidal   kills bacteria  
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fungicidal   kills fungi  
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contaminated   not sterile  
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sanitization   not sterilization, just clean  
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microbiostatic   causes tiny life forms not to grow [ex. - refrigerator]  
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pharmacology   study of drugs  
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antimicrobial agents   drugs used to treat infections  
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antibiotic   metabolic production of one microorganism that kills or inhibits the growth of another microbe  
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selective toxicity   selective inhibition of the growth of the microorganism without damage to the host  
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broad spectrum antibiotic   active against several types of microbes  
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narrow spectrum antibiotic   active against one or few types of microbes [best for treatment]  
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physical control of microbes   heat, filtration, uv light, x-rays, gamma rays, dehydration, cold  
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chemical control of microbes   disinfectant, antiseptic, chlorine, alcohol, soap, hydrogen peroxide  
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only way to destroy endspores   autoclave [pressure and steam]  
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penicillin...   acts by inhibiting transpeptidases  
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pathogenesis   the ability to cause disease is dependent on the ability to overcome challenges  
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different reservoirs   human, animal, environment  
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portals of entry   skin, nose, eye, mouth, urethra, vagina, placenta  
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ID50   infectious dose for 50% test animals [the lower it is, the more likely it is to cause disease]  
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modes of transmission   respiratory droplets, fomites, body contact, fecal-oral, arthropod vectors, airborne, parenteral  
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portals of exit   nose, mouth, anus, genitals, blood  
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nosocomial infections are...   healthcare associated infections, acquired in a hospital  
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types of nosocomial infections   MRSA, C. diff, pseudomonas aeruginosa, yeast, fungus, klebisella, E. coli  
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lines of defense against infection   non-specific surface, non-specific interior, immune  
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inflammation   pain, redness, swelling, heat  
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antigen   foreign substance that triggers immune response in host  
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antibody   protein produced by B lymphocytes that binds to antigens freely  
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where B cells mature   bone marrow  
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where T cells mature   thymus  
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IgG antibody   activates component cascades  
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IgA antibody   protects mucous membranes  
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IgM antibody   primary immune response  
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IgD antibody   signals B cells  
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IgE antibody   stimulates degranulation of basophils, eosinophils, and mast cells  
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the ability to mount an efficient secondary antibody response depends on   memory T & B cells  
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T lymphocyte stimulation leads to a type of immunity called   cell-mediated immunity  
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the call that matures in the thymus gland   is responsible for cell-mediated immunity  
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the first antibody produced in a primary antibody response is   IgM  
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which of the following is the fastest response to an antigen?   secondary immune response  
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which is not an effect of complement activation?   enhanced T lymphocyte activity through thymus gland interaction  
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the uniqueness of an individual is defined in part by   MHC proteins on the surfaces of individual cells [important in transplants]  
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which is the best definition for innate immunity?   several non-specific defenses present from birth  
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neutrophils are those leukocytes that function   phagocytes in body resistance  
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when clotting agents are removed from the blood   serum  
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link between macrophages & neutrophils   are phagocytes  
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which is not a lymphocyte?   monocytes  
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which leukocytes are involved in acquired immunity?   B lymphocytes & T lymphocytes  
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where is normal flora not found?   the blood  
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degree to which organism is able to cause disease   phagogenecity  
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botulism, tetanus, and diphtheria are distinguished by   production of endotoxins  
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endotoxin shock may be observed to follow   antibiotic treatment of a disease due to GRAM NEGATIVE bacteria  
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disease constantly present at low level in an area   endemic  
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which is not a common cause of nosocomial infections?   inefficient air handling mechanisms  
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a substance that has been pasteurized   is not considered sterile  
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two draw backs to penicillin   allergic reactions and drug resistance  
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MRSA is resistant to what?   methicillin  
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cephlosporin & penicillin antibiotics   act on cell wall of bacteria  
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nyastatin is recommended for   candida albicans of intestines / oral cavity  
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kirby-bauer test is useful for determining   which antibiotic should be used  
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