Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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| What is substrate level phosphorylation? | Transferring a phosphate to an ADP, directly from another molecule
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| What is oxidative phosphorylation? | The production of ATP, is driven by a proton gradient
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| Where does glycolysis occur? | Cytoplasm
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| Glucose + ATP -> _____ + ADP + H(+) | Glucose - 6 - phosphate
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| What enzyme is used to convert glucose to glucose -6 - phosphate? | Hexokinase
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| What is so significant about G-6-P? | Charged molecule which is prevented from leaving the cell
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| Glucose - 6 - phosphate -> _____ | Fructose -6 -phosphate
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| What enzyme catalyses G-6-P to F-6-P? | Phosphoglucose isomerase
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| Fructose-6-phosphate + ATP -> _______ +ADP + H(+) | Fructose 1,6-bisphophate
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| What enzyme catalyses the conversion of F-6-P to F-1,6-bP? | Phosphofructokinase
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| Fructose -1,6- bisphosphate <-> Glyceraldehyde - 3 - phosphate + _____ | Dihydroxyacetone phosphate
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| Dihydroxyacetone <-> _____ | Glyceraldehyde-3-phosphate
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| Glyceraldehyde-3-phosphate + NAD+ + Pi <-> ____ + NADH + H+ | 1,3-bisphosphateglycerate
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| 1,3-bisphosphateglycerate + ADP <-> ______ + ATP | 3-phosphateglycerate
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| 3-phosphoglycerate <-> _____ | 2-phosphoglycerate
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| 2-phosphoglycerate <-> ____+ H2O | Phosphoenolpyruvate
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| Phosphoenolpyruvate + ADP + H+ -> ___ + ATP | Pyruvate
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| What are the products of glycolysis? | 2x Pyruvate
2x ATP (net)
2x NADH
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| What are the three fates of pyruvate? | Lactate
Ethanol
CO2 and water in oxidative phosphorylation
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| What inhibits hexokinase? | Glucose - 6- phosphate
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| What activates phosphofructokinase? | AMP, ADP & fructose 1,6 - bisphosphate
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| What inhibits phosphofructokinase? | ATP & Citrate
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| What activates pyruvate kinase? | Fructose 1,6- bisphosphate
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| What inhibits pyruvate kinase? | ATP & acetyl CoA
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| Where does the TCA cycle & link reaction occur? | Matrix of the mitochondria
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| What happens when pyruvate is added to coA to produce acetyl co-enzyme A ? | CO2 is lost, and NADH is produced
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| Oxaloacetate + Acetyl CoA -> ____ | Citrate
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| Citrate <-> ____ | Isocitrate
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| Isocitrate <-> _____ | Alpha ketoglutarate
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| When isocitrate is converted to alpha ketoglutarate, what molecules are produced? | CO2 & NADH
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| Alpha ketoglutarate -> ____ | Succinyl CoA
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| When alpha ketoglutarate is converted to succinyl CoA, what is produced? | CO2 and NADH
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| Succinyl CoA -> _____ + CoA | Succinate
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| What is produced when Succinyl CoA is converted to succinate? | ATP/GTP
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| Succinate <-> _____ | Fumurate
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| What is produced when succinate is converted to fumurate? | FADH2
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| Fumurate <-> ____ | Malate
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| Malate <-> ______ | Oxaloacetate
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| When malate is converted to oxaloacetate, what is produced? | NADH
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| What inhibits citrate synthase? | ATP
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| What inhibits alpha ketoglutarate dehydrogenase complex? | ATP and succinyl CoA
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| What stimulates isocitrate dehydrogenase? | NAD+, ATP, Mg2+
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| What inhibits isocitrate dehydrogenase? | ATP, NADH
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| Where does the electron transport chain occur? | Inner mitochondrial membrane
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| What is special about succinate dehydrogenase in terms of where it is? | It is found in complex II
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