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ASA, NITRO, LIDO, O2, BENADRYL

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Question
Answer
Nitroglycerin GENERIC NAME   Nitroglycerin  
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Nitroglycerin BRAND NAME   Nitrostat  
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Nitroglycerin CLASS   Vasodilator  
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Nitroglycerin MECHANISM OF ACTION   Relaxes vascular smooth muscles, dilating peripheral arteries and veins  
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Nitroglycerin INDICATIONS   Angina, Myocardial ischemia associated with cocaine intoxication.  
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Nitroglycerin CONTRAINDICATIONS   Hypotension, severe bradycardia or tachycardia, any ED drugs,  
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Nitroglycerin ADVERSE REACTIONS   HA, Hypotension, Bradycardia, lightheadedness, flushing  
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Nitroglycerin INCOMPATABILITIES/DRUG INTERACTIONS   Incompatible with other IV drugs.  
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Nitroglycerin ADULT DOSE/ROUTE   1 Tablet (0.3-0.4mg) or 1 Spray (0.4mg) sublingual every 5 minutes, up to 3 doses.  
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Nitroglycerin PEDS DOSE/ROUTE   Not recommended  
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Nitroglycerin ONSET OF ACTION   3 minutes  
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Nitroglycerin PEAK EFFECTS   10 minutes  
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Nitroglycerin DURATION OF ACTION   30 minutes  
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Nitroglycerin AZ DRUG BOX SUPPLY RANGE   1 bottle tablets, 1 bottle spray  
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Oxygen GENERIC NAME   None  
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Oxygen BRAND NAME   Oxygen  
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Oxygen CLASS   Naturally occurring atmospheric gas  
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Oxygen MECHANISM OF ACTION   Reverses Hypoxemia  
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Oxygen INDICATIONS   hypoxemia, CP, respiratory insufficiency, carbon monoxide poisoning, decreased tissue oxygenation, decreased LOC.  
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Oxygen CONTRAINDICATIONS   Hyperventilation.  
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Oxygen ADVERSE REACTIONS   Retrolental fibroplasia if given in high concentrations to premature infants (maintain 30-40%)  
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Oxygen NOTES ON ADMINISTRATION   Never with hold  
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Oxygen INCOMPATABILITIES/DRUG INTERACTIONS   None.  
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Oxygen DOSE/ROUTE Adult and Pediatric   10-15L via NRB, or 2-6L via NC.  
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Oxygen ONSET OF ACTION   Immediate  
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Oxygen PEAK EFFECTS   N/A  
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Oxygen DURATION OF ACTION   2 minutes  
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Oxygen AZ DRUG BOX SUPPLY RANGE   13 cubic feet  
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Diphenhydramine GENERIC NAME   Diphenhydramine  
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Diphenhydramine BRAND NAME   Benadryl  
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Diphenhydramine CLASS   Antihistamine; anticholinergic  
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Diphenhydramine MECHANISM OF ACTION   Blocks cellular histamine receptors; decreases vasodilation; decreases motion sickness.  
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Diphenhydramine INDICATIONS   allergic reactions, anaphylaxis, acute dystonic reactions (phenothiazines).  
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Diphenhydramine CONTRAINDICATIONS   Asthma, pregnancy, htn, narrow angle glaucoma, (MAOIs)  
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Diphenhydramine ADVERSE REACTIONS   Sedation. Hypotension, sz’s, vomiting, palpitations, arrhythmias. NOTES ON ADMINISTRATION  
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Diphenhydramine DOSE/ROUTE Adult   25-50mg IV, IM, or PO.  
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Diphenhydramine Pediatric DOSE/ROUTE   1-2 mg/kg IV. IO slowly, or IM. If given PO  
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Diphenhydramine ONSET OF ACTION   30 minutes  
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Diphenhydramine PEAK EFFECTS   1 hour  
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Diphenhydramine DURATION OF ACTION   3-12 hours.  
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Diphenhydramine AZ DRUG BOX SUPPLY RANGE   50 mg.  
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Lidocaine GENERIC NAME   Lidocaine Hydrochloride  
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Lidocaine BRAND NAME   Xylocaine  
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Lidocaine CLASS   Antiarrhythmic  
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Lidocaine MECHANISM OF ACTION   Decreases automaticity by slowing the rate of phase 4 depolarization  
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Lidocaine INDICATIONS   Alternative to amiodarone in cardiac arrest from V-fib/Pulseless V-tach, stable monomorphic V-tach, stable polymorphic V-tach with normal baseline QT interval.  
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Lidocaine CONTRAINDICATIONS   av blocks, bleeding, thrombocytopenia.  
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Lidocaine ADVERSE REACTIONS   Slurred speech, seizures, Bradycardia, hypotension, cardiac arrest, and arrhythmias.  
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Lidocaine NOTES ON ADMINISTRATION   Exceedingly high doses can result in coma or death.  
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Lidocaine INCOMPATABILITIES/DRUG INTERACTIONS   Metabolic clearance is decreased in patients with liver disease or in patients taking beta blockers.  
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Lidocaine DOSE/ROUTE Adult cardiac arrest from V-Fib/Pulseless V-tach, Initial dose   1-1.5 mg/kg IV/IO.  
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Lidocaine DOSE/ROUTE Adult maintenance infusion   1-4 mg/min. Can be diluted in D5W or NS  
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Lidocaine DOSE/ROUTE Pediatric IV/IO dose   1 mg/kg rapid IV/IO push. Max 100 mg  
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Lidocaine ONSET OF ACTION   3 minutes  
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Lidocaine PEAK EFFECTS   10 minutes  
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Lidocaine DURATION OF ACTION   2 hours  
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Lidocaine AZ DRUG BOX SUPPLY RANGE   3 prefilled syringes, total of 300 mg , 1g vials or premixed infusion, total of 2g  
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ASA GENERIC NAME   ASA  
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ASA BRAND NAME   Aspirin  
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ASA CLASS   Platelet inhibitor, anti-inflammatory agent  
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ASA MECHANISM OF ACTION   Prostaglandin inhibition  
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ASA INDICATIONS   Any symptom suggestive of a MI, Fever, inflammation.  
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ASA CONTRAINDICATIONS   Hypersensitivity, gi bleed, active ulcer bleed.  
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ASA ADVERSE REACTIONS   Angioedema, bronchospasm, bleeding, N/V  
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ASA NOTES ON ADMINISTRATION   Not recommended for peds  
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ASA INCOMPATABILITIES/DRUG INTERACTIONS   Use with caution in patients allergic to NSAID’s  
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ASA ADULT DOSE/ROUTE   325mg  
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ASA ONSET OF ACTION   45 minutes  
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ASA PEAK EFFECTS   Variable  
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ASA DURATION OF ACTION   Variable  
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ASA AZ DRUG BOX SUPPLY RANGE   324mg.  
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Benadryl NOTES ON ADMINISTRATION   Not used in infants or in pregnancy  
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Benadryl INCOMPATABILITIES/DRUG INTERACTIONS   Potentiates effects of alcohol  
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