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Drug profiles
ASA, NITRO, LIDO, O2, BENADRYL
| Question | Answer |
|---|---|
| Nitroglycerin GENERIC NAME | Nitroglycerin |
| Nitroglycerin BRAND NAME | Nitrostat |
| Nitroglycerin CLASS | Vasodilator |
| Nitroglycerin MECHANISM OF ACTION | Relaxes vascular smooth muscles, dilating peripheral arteries and veins |
| Nitroglycerin INDICATIONS | Angina, Myocardial ischemia associated with cocaine intoxication. |
| Nitroglycerin CONTRAINDICATIONS | Hypotension, severe bradycardia or tachycardia, any ED drugs, |
| Nitroglycerin ADVERSE REACTIONS | HA, Hypotension, Bradycardia, lightheadedness, flushing |
| Nitroglycerin INCOMPATABILITIES/DRUG INTERACTIONS | Incompatible with other IV drugs. |
| Nitroglycerin ADULT DOSE/ROUTE | 1 Tablet (0.3-0.4mg) or 1 Spray (0.4mg) sublingual every 5 minutes, up to 3 doses. |
| Nitroglycerin PEDS DOSE/ROUTE | Not recommended |
| Nitroglycerin ONSET OF ACTION | 3 minutes |
| Nitroglycerin PEAK EFFECTS | 10 minutes |
| Nitroglycerin DURATION OF ACTION | 30 minutes |
| Nitroglycerin AZ DRUG BOX SUPPLY RANGE | 1 bottle tablets, 1 bottle spray |
| Oxygen GENERIC NAME | None |
| Oxygen BRAND NAME | Oxygen |
| Oxygen CLASS | Naturally occurring atmospheric gas |
| Oxygen MECHANISM OF ACTION | Reverses Hypoxemia |
| Oxygen INDICATIONS | hypoxemia, CP, respiratory insufficiency, carbon monoxide poisoning, decreased tissue oxygenation, decreased LOC. |
| Oxygen CONTRAINDICATIONS | Hyperventilation. |
| Oxygen ADVERSE REACTIONS | Retrolental fibroplasia if given in high concentrations to premature infants (maintain 30-40%) |
| Oxygen NOTES ON ADMINISTRATION | Never with hold |
| Oxygen INCOMPATABILITIES/DRUG INTERACTIONS | None. |
| Oxygen DOSE/ROUTE Adult and Pediatric | 10-15L via NRB, or 2-6L via NC. |
| Oxygen ONSET OF ACTION | Immediate |
| Oxygen PEAK EFFECTS | N/A |
| Oxygen DURATION OF ACTION | 2 minutes |
| Oxygen AZ DRUG BOX SUPPLY RANGE | 13 cubic feet |
| Diphenhydramine GENERIC NAME | Diphenhydramine |
| Diphenhydramine BRAND NAME | Benadryl |
| Diphenhydramine CLASS | Antihistamine; anticholinergic |
| Diphenhydramine MECHANISM OF ACTION | Blocks cellular histamine receptors; decreases vasodilation; decreases motion sickness. |
| Diphenhydramine INDICATIONS | allergic reactions, anaphylaxis, acute dystonic reactions (phenothiazines). |
| Diphenhydramine CONTRAINDICATIONS | Asthma, pregnancy, htn, narrow angle glaucoma, (MAOIs) |
| Diphenhydramine ADVERSE REACTIONS | Sedation. Hypotension, sz’s, vomiting, palpitations, arrhythmias. NOTES ON ADMINISTRATION |
| Diphenhydramine DOSE/ROUTE Adult | 25-50mg IV, IM, or PO. |
| Diphenhydramine Pediatric DOSE/ROUTE | 1-2 mg/kg IV. IO slowly, or IM. If given PO |
| Diphenhydramine ONSET OF ACTION | 30 minutes |
| Diphenhydramine PEAK EFFECTS | 1 hour |
| Diphenhydramine DURATION OF ACTION | 3-12 hours. |
| Diphenhydramine AZ DRUG BOX SUPPLY RANGE | 50 mg. |
| Lidocaine GENERIC NAME | Lidocaine Hydrochloride |
| Lidocaine BRAND NAME | Xylocaine |
| Lidocaine CLASS | Antiarrhythmic |
| Lidocaine MECHANISM OF ACTION | Decreases automaticity by slowing the rate of phase 4 depolarization |
| Lidocaine INDICATIONS | Alternative to amiodarone in cardiac arrest from V-fib/Pulseless V-tach, stable monomorphic V-tach, stable polymorphic V-tach with normal baseline QT interval. |
| Lidocaine CONTRAINDICATIONS | av blocks, bleeding, thrombocytopenia. |
| Lidocaine ADVERSE REACTIONS | Slurred speech, seizures, Bradycardia, hypotension, cardiac arrest, and arrhythmias. |
| Lidocaine NOTES ON ADMINISTRATION | Exceedingly high doses can result in coma or death. |
| Lidocaine INCOMPATABILITIES/DRUG INTERACTIONS | Metabolic clearance is decreased in patients with liver disease or in patients taking beta blockers. |
| Lidocaine DOSE/ROUTE Adult cardiac arrest from V-Fib/Pulseless V-tach, Initial dose | 1-1.5 mg/kg IV/IO. |
| Lidocaine DOSE/ROUTE Adult maintenance infusion | 1-4 mg/min. Can be diluted in D5W or NS |
| Lidocaine DOSE/ROUTE Pediatric IV/IO dose | 1 mg/kg rapid IV/IO push. Max 100 mg |
| Lidocaine ONSET OF ACTION | 3 minutes |
| Lidocaine PEAK EFFECTS | 10 minutes |
| Lidocaine DURATION OF ACTION | 2 hours |
| Lidocaine AZ DRUG BOX SUPPLY RANGE | 3 prefilled syringes, total of 300 mg , 1g vials or premixed infusion, total of 2g |
| ASA GENERIC NAME | ASA |
| ASA BRAND NAME | Aspirin |
| ASA CLASS | Platelet inhibitor, anti-inflammatory agent |
| ASA MECHANISM OF ACTION | Prostaglandin inhibition |
| ASA INDICATIONS | Any symptom suggestive of a MI, Fever, inflammation. |
| ASA CONTRAINDICATIONS | Hypersensitivity, gi bleed, active ulcer bleed. |
| ASA ADVERSE REACTIONS | Angioedema, bronchospasm, bleeding, N/V |
| ASA NOTES ON ADMINISTRATION | Not recommended for peds |
| ASA INCOMPATABILITIES/DRUG INTERACTIONS | Use with caution in patients allergic to NSAID’s |
| ASA ADULT DOSE/ROUTE | 325mg |
| ASA ONSET OF ACTION | 45 minutes |
| ASA PEAK EFFECTS | Variable |
| ASA DURATION OF ACTION | Variable |
| ASA AZ DRUG BOX SUPPLY RANGE | 324mg. |
| Benadryl NOTES ON ADMINISTRATION | Not used in infants or in pregnancy |
| Benadryl INCOMPATABILITIES/DRUG INTERACTIONS | Potentiates effects of alcohol |
Created by:
klindley
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