Pharm Test 3
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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| Enalapril | Vasotec
Ace Inhibitor
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| Enalapril Indications | HTN
HF
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| Enalapril Interactions | Other HTN meds = additive
Thiazide = increase K loss
Increase lithium toxicity
NSAIDs= decrease effects = Increase BP
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| Enalapril CI | Hypersensitivity
Pregnancy/Lactation
BBW= Fetal injury/death
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| Enalapril SE | OTH
1st dose syncope
HA/Dizziness
LIFETHREATENING: angioedema, neutropenia, agranulocytosis
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| Nifedipine | Procardia
CCB
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| Nifedipine Indications | HTN
Angina
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| Nifedipine Interactions | Other HTN meds= additive
BB= increase risk of HF
Increase Dig toxocity
Alcohol=syncope
Grapefruit juice=enhance absorption= additive
Melatonin=counter effects = increase BP/HR
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| Nifedipine CI | Hypersensitivity
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| Nifedipine SE | HA
Dizziness
Peripheral Edema
Flushing
*Immediate action forms= reflex tachycardia
DC gradually=rebound hypotension
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| Doxazosin | Cardura
A Blocker
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| Doxazosin Indications | Urinary Retention--> BPH & HTN
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| Doxazosin Interactions | Other HTN meds= additive
Climetidine=increase half life
Viagra (phosphodiesterase inhib) = additive
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| Doxazosin CI | Hypersensitivity
Hypotensive
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| Doxazosin SE | Dizziness
Dyspnea
Athenia
HA
Hypotension
Somnolence
OTH
1st does phenomenon
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| Metoprolol | Lopressor
BB
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| Metoprolol Indications | HTN
HF
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| Metoprolol Interactions | Diuretics + antiHTN= mask hypoglycemia
NSAID=decrease effect
Digoxin= increase risk of bradycardia
Oral contraceptives = increase effects
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| Metoprolol CI | Hypersensitivity
MI= serious sinus bradycardia HR <45/ SBP <100
Mod-Severe HF
Asthma
Cardiogenic shock
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| Metoprolol SE | Diminished sexual function
Insomnia
Unusual weakness/fatigue
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| Losartan | Cozaar
ARB
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| Losartan Indication | HTN
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| Losartan Interactions | NSAIDs= decrease
K diuretics = increase K
Diuretics/ antiHTN= additive
Herbal: ephedra, licorice, ginseng= additive
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| Losartan CI | Hypersensitivity
Renal/Hepatic impairment
K supplements- hyperkalemia
Hx of angioedema
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| Losartan SE | HA
Dizziness
OTH
Rash
Diarrhea
AE= angioedema, acute renal failure, 1st dose phenomenon, fetal toxicity, neonatal mortality
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| Hydralazine | Apresoline
Vasodilator
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| Hydralazine Indication | HTN
HF
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| Hydralazine Interactions | Other HTN meds= additive
NSAID= decrease
False coombs test
Hawthorn= decrease
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| Hydralazine CI | Angina
Rheumatic Heart Dz
MI
Tachycardia
Lupus= worsens
Abrupt wd= rebound HTN
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| Hydralazine SE | HA
Tachycardia
Palpitations
Flushing
Nausea
Diarrhea
BB=counteract reflex tachycardia
*Na/fluid retenion= serious AE
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| Furosemide | Lasix
Loop diuretic
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| Furosemide Indications | HTN
HF (if fluid retention present)
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| Furosemide Interactions | Cardiac glycosides (dig)= hypokalemia
Corticosteroids, amp B, K depleting drugs = hypokalemia
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| Furosemide CI | Hypersensitivty
Anuria
Hepatic Coma
Severe fluid/electrolyte depletion
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| Furosemide SE | Hypokalemia
Dehydration
Hypotension
OTH
*Ototoxicity
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| Spironolactone | Aldactone
K sparing diuretic, Aldosterone antagonist
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| Spironolactone Indications | HTN
Edema- HF
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| Spironolactone Interactions | Ammonium chloride= acidosis
ASA, NSAIDs= decrease
Digoxin= decrease effects of dig
K supplements, ACE inhibitors, ARBS= hyperkalemia
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| Spironolactone CI | Anuria
Renal impairment
Hyperkalemia
Pregnancy/Lactation
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| Spironolactone SE | Hyperkalemia
Women: menstrual irregularities, hirsutism, breast tenderness
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| Hydrochlorothiazide | Microzide
Thiazide diuretic
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| Hydrochlorothiazide Indication | HTN
Edema-HF
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| Hydrochlorothiazide Interactions | Other HTN med= additive
Decrease effectivess of anticoag, sulfonylureas, antidiabetic drugs
Cholestryamine and Colestipol= decrease absorption
NSAIDS= renal toxicity
Corticosteroids, amp B = increase K loss= hypokalemia
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| Hydrochlorothiazide CI | Anuria
Hypersensitivity
Pre-eclampsia
Eclampsia
Pregnancy induced HTN
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| Hydrochlorothiazide SE | Na/K imbalances
Teach increase K in diet
Gout attacks= due to hyperuricemia
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| Digoxin | Lanoxin
Cardiac Glycoside
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| Digoxin Indication | HF
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| Digoxin Interactions | Diuretics=hypokalemia= dysrhythmias
Ace inhib, spironolactone, ARB= hyperkalemia
Positive inotropic drug= additive
BB= additive bradycardia
Antacids, cholesterol lowering drugs= decrease absorption
Ginseng= increase risk of dig tox
Ma huang, ephedra
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| Lisinopril | Prinivil
Ace Inhib
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| Lisinopril Indications | HTN
HF
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| Lisinopril Interactions | NSAIDS= decrease
Diuretic= additive
K diuretic= hyperkalemia
Increase lithium levels= toxicity
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| Lisinopril CI | Hyperkalemia
Angioedema
Pregnancy
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| Lisinopril SE | Cough
HA
Dizziness
OTH
Rash
Hyperkalemia
Taste disturbances
Chest pain
N/V/D
Angioedema= SERIOUS
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