GERD Medications
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| Proton Pump Inhibitor | decrease HCl acid secretion by inhibiting the proton pump responsible for the secretion of H and decrease irritation of the esophageal and gastric mucosa
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| Histamine (H2)-Receptor Blockers | Blocks the action of histamine on the H2 receptors to decrease HCl acid secretion, decrease conversion of pepsinogen to pepsin, and irritation of the esophageal and gastric mucosa
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| Prokinetic Agents | Blocks effect of dopamine, increases gastric mobility and emptying, and reduces reflux
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| Antiulcer, Protectants | Acts to form a protective layer and serves as a barrier against acid, bile salts, and enzymes in the stomach
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| Cholinergic | Increases LES pressure, improves esophageal emptying, and increases gastric emptying
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| Antacids, Acid Neutralizers | Neutralizes HCl acid and is taken 1-3 hours after meals and at bedtime
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| Prostaglandin (Synthetic) | Protects lining of the stomach, increases production of gastric mucus and mucosal secretion of bicarbonate, and decreases HCl acid secretion
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| Dexlansoprazole (Dexilant) | proton pump inhibitor
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| Esomeprazole (Nexium) | proton pump inhibitor
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| Lansoprazole (Prevacid) | proton pump inhibitor
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| Omeprazole (Prilosec) | proton pump inhibitor
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| Pantoprazole (Protonix) | proton pump inhibitor
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| Rabeprazole (AcipHex) | proton pump inhibitor
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| Cimetidine (Tagamet) | Histamine (H2)- receptor blocker
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| Famotidine (Pepcid) | Histamine (H2)- receptor blocker
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| Nizatidine (Axid) | Histamine (H2)- receptor blocker
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| Ranitidine (Zantac) | Histamine (H2)- receptor blocker
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| Metoclopramide (Reglan) | Prokinetic agent
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| Sucralfate (Carafate) | Antiulcer, protectant
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| Bethanechol (Urecholine) | Cholinergic
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| Aluminum carbonate (Basaljel) | single substance antacid, acid neutralizer
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| Aluminum hydroxide (Amphojel) | single substance antacid, acid neutralizer
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| Calcium carbonate (Tums, Tiralac) | single substance antacid, acid neutralizer
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| Magnesium oxide (MagOx) | single substance antacid, acid neutralizer
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| Sodium bicarbonate (Alka-Seltzer) | single substance antacid, acid neutralizer
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| Sodium citrate (Bicitra) | single substance antacid, acid neutralizer
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| Gelusil, Maalox, Mylanta, Aludrox aluminum/magnesium trisilicate (Gaviscon) | Aluminum and Magnesium antacid, acid neutralizer
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| Misoprostol (Cytotec) | Prostaglandin (synthetic)
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