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GERD Medications

TermDefinition
Proton Pump Inhibitor decrease HCl acid secretion by inhibiting the proton pump responsible for the secretion of H and decrease irritation of the esophageal and gastric mucosa
Histamine (H2)-Receptor Blockers Blocks the action of histamine on the H2 receptors to decrease HCl acid secretion, decrease conversion of pepsinogen to pepsin, and irritation of the esophageal and gastric mucosa
Prokinetic Agents Blocks effect of dopamine, increases gastric mobility and emptying, and reduces reflux
Antiulcer, Protectants Acts to form a protective layer and serves as a barrier against acid, bile salts, and enzymes in the stomach
Cholinergic Increases LES pressure, improves esophageal emptying, and increases gastric emptying
Antacids, Acid Neutralizers Neutralizes HCl acid and is taken 1-3 hours after meals and at bedtime
Prostaglandin (Synthetic) Protects lining of the stomach, increases production of gastric mucus and mucosal secretion of bicarbonate, and decreases HCl acid secretion
Dexlansoprazole (Dexilant) proton pump inhibitor
Esomeprazole (Nexium) proton pump inhibitor
Lansoprazole (Prevacid) proton pump inhibitor
Omeprazole (Prilosec) proton pump inhibitor
Pantoprazole (Protonix) proton pump inhibitor
Rabeprazole (AcipHex) proton pump inhibitor
Cimetidine (Tagamet) Histamine (H2)- receptor blocker
Famotidine (Pepcid) Histamine (H2)- receptor blocker
Nizatidine (Axid) Histamine (H2)- receptor blocker
Ranitidine (Zantac) Histamine (H2)- receptor blocker
Metoclopramide (Reglan) Prokinetic agent
Sucralfate (Carafate) Antiulcer, protectant
Bethanechol (Urecholine) Cholinergic
Aluminum carbonate (Basaljel) single substance antacid, acid neutralizer
Aluminum hydroxide (Amphojel) single substance antacid, acid neutralizer
Calcium carbonate (Tums, Tiralac) single substance antacid, acid neutralizer
Magnesium oxide (MagOx) single substance antacid, acid neutralizer
Sodium bicarbonate (Alka-Seltzer) single substance antacid, acid neutralizer
Sodium citrate (Bicitra) single substance antacid, acid neutralizer
Gelusil, Maalox, Mylanta, Aludrox aluminum/magnesium trisilicate (Gaviscon) Aluminum and Magnesium antacid, acid neutralizer
Misoprostol (Cytotec) Prostaglandin (synthetic)
Created by: parnell_hb