Ondansetron
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| GENERIC NAME | Ondansetron
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| Ondansetron BRAND NAME | Zofran
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| Ondansetron CLASS | Antiemetic agent
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| Ondansetron MECHANISM OF ACTION | Selectively blocks serotonin 5-HT3 receptors located in the CNS at the chemoreceptor trigger zone and in the peripheral nervous system on nerve-terminals of the vagus nerve
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| Ondansetron INDICATIONS | N/V
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| Ondansetron CONTRAINDICATIONS | Hypersensitivity,Use with caution in patients with hepatic impairment
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| Ondansetron ADVERSE REACTIONS | CNS; Headache, malaise, fatigue, dizziness, fever, sedation, extrapyramidal syndrome, Cardiovascular; Chest pain, arrhythmias Respiratory; Hypoxia, GI & Hepatic; Diarrhea, constipation, abdominal pain, xerostomia, decreased appetite, Skin; Rash
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| Ondansetron INCOMPATABILITIES/DRUG INTERACTIONS | Inducers or inhibitors of P450 drug metabolizing enzymes may alter the clearance of Ondansetron. No dosage adjustment is recommended.
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| Ondansetron DOSE/ROUTE, Adult Dosage | 4 – 8 mg IV slow push over 2 – 5 minutes 8 mg PO ODT or tablet
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| Ondansetron Pediatric Dosage | (1 month to 12 years old) Greater than 40 kg- 4 mg IV slow push over 2 – 5 minutes; Less than 40 kg- 0.1 mg/kg IV slow push over 2 – 5 minutes; 4-12 years old 4 mg PO ODT or ODT
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| Ondansetron ONSET OF ACTION | Unknown but maybe 10-30 minutes
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| Ondansetron PEAK EFFECTS | unknown
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| Ondansetron DURATION OF ACTION | Half life ~ 4 hours. Duration unknown
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| Ondansetron AZ DRUG BOX SUPPLY RANGE | 8mg
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Created by:
klindley
Popular Paramedic/EMT sets