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CH11 audesirk VOCAB

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Question
Answer
WHEN does DNA replication occur?   S-phase of interphase  
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WHERE does DNA replication occur?   nucleus  
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What is the key feature that allows DNA to be copied?   the pairing of nitrogen bases in DNA  
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Who discovered that harmless bacteria can be "transformed" into pneumonia-causing bacteria?   F. Griffith  
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Who identified that DNA is the transforming factor?   Avery & Associates  
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Who identified that the genetic material of a virus is not protein?   Hershey & Chase  
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Who used x-ray diffraction to determine that DNA is a helical molecule?   Franklin & Wilkins  
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Who identified that the amount of adenine equals the amount of thymine in DNA and that the amount of guanine equals the amount of cytosine in DNA? (chargaff's rules... A=T and G=C)   Chargaff  
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Who pulled the data together to construct a 3-dimensional model of DNA as a double helix in which two strands were wound around each other?   Watson & Crick  
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Who received the Nobel Prize in 1962?   Watson & Crick and Wilkins  
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Who died in 1958?   Franklin  
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What is the structure of DNA?   4 nucleotides  
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Each nucleotide has a __________, a ______________, and a ___________.   phosphate; 5 carbon sugar; nitrogen containing base  
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What are the 4 bases?   adenine, guanine, thymine, cytosine  
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___________ (A&G) are double ring bases- larger in size.   Purines  
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_________ (T&C) are single ring bases- smaller in size.   Pyrimidines  
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DNA is a ____________.   double helix  
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A double helix is a ____________.   twisted ladder  
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The ___________________ make up the ___________ (sides) of the molecule.... held together with __________ bonds (strong).   sugars & phosphates; backbones; covalent  
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The _________________ make up the ___________ (rungs) and are held together with _____________ bonds (easily broken).   base pairs; middle; hydrogen  
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A bonds to T with _ hydrogen bonds.   2  
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G bonds to C with _ hydrogen bonds.   3  
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The ________ side of the DNA helix reads 3' to _'. This is the _____________ and also reads _____ to right, _______ to top.   right; 5; hydroxylon sugar; left; bottom  
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The ___________ side of the DNA helix reads 5' to _'. This is the ________________ and also reads ________ to left, ___ to bottom.   left; 3; phosphate end; right; top  
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All "____" (combo of bases (codons)) have only _ letters.   words; 3  
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How letters are there in the bases alphabet?   4  
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4 cubed = ___ (how many combos of codons)   64  
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What does DNA replication produce?   2 double helices  
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Both double helices produces have what?   1 original strand and 1 new strand  
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Producing 1 original and 1 new strand is called what?   semiconservative replication  
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Replication involves what 3 major actions and enzymes?   DNA helicase, DNA polymerase, DNA ligase  
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This enzyme involved in replication separates the parent strands.   DNA helicase  
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This enzyme involved in replication synthesizes new DNA strands and proofreads strands.   DNA polymerase  
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This enzyme involved in replication joins segments to make the daughter strands.   DNA ligase  
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The result of DNA helicase breaking the hydrogen bonds between the complementary parental DNA strands:   unwound sections of DNA strands  
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Name this part of DNA replication: a place at the edge of the replication bubble where the parental DNA strands have not yet been unwound... where DNA polymerase adds complementary bases to parts that are unwound   replication fork  
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If there are no mistakes during replication: 2 _____ DNA helices are formed... ______ to the _________ and to each ______.   identical; identical; original; other  
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_____________ and other enzymes "proofread" the strands for accuracy and fixes most errors.   DNA polymerase  
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________/ 100 million to 1 billion base pairs   1 mistake  
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The mistakes (mutations) can be:   good, bad, or null  
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Sources of error in DNA:   chemicals, UV rays, aging  
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____ mutations are the driving force of ____________.   good; evolution  
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