Cell Bio
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| In the cell cycle, _______ is when the cell grows and carries out normal metabolism and organelles duplicate. | show 🗑
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| show | S
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| show | G2
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| Interphase includes what phases? | show 🗑
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| show | interphase
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| ___________ is dispersed in interphase for transcription and replication. | show 🗑
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| show | histones, centrioles
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| show | chromatin, chromatid, chromosomes, transcription, replication
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| If there is no G1 or G2 and only S-phase, what happens to the cells? What are examples? | show 🗑
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| If a cell is stuck in G1 or G0, what happens to the cell? What are examples? | show 🗑
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| If a cell is inducible, it progresses from _______ to ________ if triggered. What are examples? | show 🗑
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| The mitotic spindle contains two ________, each of which has two _________. | show 🗑
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| show | Chromatin
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| __________ are threadlike strands that are composed of the nuclear DNA of eukaryotic cells and are the carriers of genetic information | show 🗑
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| ___________ are paired, rod-shaped members of mitotic chromosomes that together represent the duplicated chromosomes formed during replication in interphase. | show 🗑
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| Metabolic labeling with 3H thymidine only happens during what? | show 🗑
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| show | S-phase and mitosis
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| show | cytoplasm of a mitotic cell
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| show | Maturation-promoting factor. protein kinase + cyclin
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| show | Kinases
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| ________ is part of the MPF complex which regulates its activity. | show 🗑
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| ___________ stimulates the progression from G1 to S-phase. _________ stimulates progression from G2 to mitosis. | show 🗑
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| Mitotic cyclin B1 accumulates in the ________ in the start of mitosis. | show 🗑
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| ______________ can act as molecular brakes to stop the cell cycle from progressing to the next step. | show 🗑
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| show | G1
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| The ________ checkpoint sees if all DNA replicated and repaired. | show 🗑
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| show | Mitosis
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| ___________ is a single set of genetic information. Single genome. | show 🗑
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| show | Diploid
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| _________ is many sets of genetic information. | show 🗑
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| _______ is the number of sets or copies of genetic information. | show 🗑
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| show | 2n2x2c
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| In G1, there are _______ chromosomes. They each consist of _______, ___________ DNA. | show 🗑
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| show | sister chromatids, double helix, 2n4x
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| show | 2 sister chromatids each.
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| Sister chromatids are held together by _________. | show 🗑
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| show | 92, 46, because each chromosome consists of two double helices
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| show | metaphase, chromatids, mitotic chromosomes
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| The goal of mitosis is to make _______ copies of cells with the same ________ and _______ content. There is no change in n. | show 🗑
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| In _________ of mitosis, chromosomal material condenses to form compact mitotic _________, which are seen to be composed of two _______ attached at the ______. | show 🗑
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| In _________ of mitosis, the cytoskeleton is _________ and the mitotic spindle is ____________. | show 🗑
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| In _________ of mitosis, the nuclear envelope disperses. | show 🗑
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| show | prometaphase, kinetochores, spindle equator
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| show | genes, alleles, aren't
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| show | number of sets
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| In _____________ of mitosis, chromosomes make sure they are attached correctly to spindle. | show 🗑
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| show | metaphase, chromosomal MTs
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| In __________ of mitosis, __________ split and chromatids separate. | show 🗑
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| show | A, MTs
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| In Anaphase _____ of mitosis, spindle poles move farther apart to get ____________ away from each other. | show 🗑
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| show | Telophase, nuclear envelope, cytokinesis
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| __________ helps to keep the two products of DNA replication (________________) together after ____ phase, through ________, and into _______. | show 🗑
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| show | prophase, centromere
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| __________ helps to compact and supercoil DNA in prophase. | show 🗑
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| show | Kinetochore
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| In humans all somatic cells have ______ chromosomes. ___________ contain 23 chromosomes. | show 🗑
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| show | homologs, sister chromatids
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| The longer the phase, the more cells you find in that phase. That's why you see most cells in ______________. Cells undergoing mitosis have more what? | show 🗑
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| show | Interphase, prophase, sister chromatids
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| show | 6
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| show | condensed chromosomes, sister chromatids
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| To stop the spindle from forming, cells are subjected to ____________. Cells condense but mitosis can't begin without the spindle. | show 🗑
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| _________ is the constricted region where the two chromatids are connected. ____________ constriction is at the centromere where the p and q arms are connected. P is the ______ arm and Q is the ________ arm. | show 🗑
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| show | Metacentric, submetacentric, acrocentric, telocentric
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| _____________ constriction is an additional constriction on one of the arms of a centromere. This is usually where the _________________ is. | show 🗑
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| show | Nucleolus, ribosomal subunits
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| The shape of a chromosome depends on where its _________________ is (the centromere, where the kinetochore will be assembled to attach to ________ at mitosis) | show 🗑
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| ___________ doesn't normally exist in cells as a separate, single-strand. It is a ______________. | show 🗑
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| show | 2n2x
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| What is a somatic cell after DNA replication? ___n___x | show 🗑
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| show | 12,12,12
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| How much DNA would be on a metaphase plate at mitosis? How much DNA would move to each pole at anaphase? How much DNA would be in each daughter cell? | show 🗑
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| _______ checkpoint assures that all chromosomes reach the spindle equator before ________ begins. | show 🗑
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| Without ________________, chromosomes tend to reorient. | show 🗑
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| If a chromosome is improperly attached, the cell stalls in _________. Once _________ is applied, cell proceeds. | show 🗑
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| show | Anaphase promoting factor, securin
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| show | Cohesin
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| In Anaphase ____, chromatids move towards the poles by shortening of the bundles of _______________ MTs that connect them to the pole to which they move. | show 🗑
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| In Anaphase A, kinetochore microtubules get ___________. | show 🗑
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| In Anaphase A, ________ is (added to/lost from?)either or both the plus and minus ends of _______________ MTs, causing shortening. | show 🗑
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| show | tubulin, added to, plus, polar
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| ______ calls for desctruction of some proteins that hold chromatids together, allowing progression from _________ to _________. | show 🗑
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| ________ binds to a regulatory protein at the end of mitosis, and calls for the destruction of mitotic ________. This enables progression into ________. | show 🗑
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Created by:
jgold37