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Chapter 8 Vocab

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Term
Definition
metabolism   the totality of an organism's chemical reactions  
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metabolic pathway   begins with a specific molecule and ends with a product  
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Catabolic pathway   release energy by breaking down complex molecules into simpler compounds  
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anabolic pathway   consumes energy to build complex molecules from simpler ones  
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Bioenergetics   the study of how energy flows through living organisms  
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Kinetic Energy   energy associated with motion  
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Heat (thermal) energy   kinetic energy associated with random movement of atoms or molecules  
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Potential Energy   energy that matter possesses because of its location or structure  
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Chemical energy   potential energy available for release in a chemical reaction  
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Thermodynamics   the study of energy transformations  
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Isolated System   unable to exchange energy or matter with its surroundings  
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Open System   energy and matter can be transferred between the system and its surroundings  
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First Law of Thermodynamics   (principle of conservation of energy) Energy can be transferred and transformed but cannot be created or destroyed.  
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Second Law of Thermodynamics   Every energy transfer or transformation increases the entropy (disorder) of the universe  
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Entropy   (disorder) entropy may decrease in an organism, but the universe's total entropy increases  
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Spontaneous processes   occur without energy input, for this to happen it must increase the entropy of the universe  
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Free Energy   measure of a system's instability, tendency to change to a more stable state  
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Free Energy Equation   deltaG = deltaH - TdeltaS  
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Equilibrium   state of maximum stability  
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Exergonic   reaction proceeds with a net release of free energy and is spontaneous  
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Endergonic   reaction absorbs free energy from its surroundings and is not spontaneous  
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Energy Coupling   the use of an exergonic process to drive an endergonic one  
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ATP   ribose sugar + adenine + 3 phosphate groups  
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Phosphorylation   transferring a phosphate group to some other molecule  
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Phosphorylated intermediate   the recipient molecule of the 3rd phosphate group  
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Enzyme   catalytic protein  
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Catalyst   a chemical agent that speeds up a reaction without being consumed by the reaction  
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Activation Energy   initial energy needed to start a chemical reaction (enzymes lower this barrier to catalyze reactions)  
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Substrate   the reactant that an enzyme acts on  
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Active site   the region on the enzyme where the substrate binds  
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Induced fit   chemical group of the active site in positions that enhance substrate ability to catalyze reactions  
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Cofactor   nonprotein enzyme help, can be organic or inorganic  
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Coenzyme   organic cofactor  
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Competitive Inhibitor   binds to the active site of an enzyme, competing with substrate  
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Noncompetitive Inhibitor   binds to another part of an enzyme, causing enzyme to change shape and make active site less effective  
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Allosteric Regulation   occurs when a regulatory molecule binds to a protein at one site and affects the proteins function at another site  
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Activator   binds to enzyme, stabilizes the active form and stimulates activity  
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Inhibitor   binds to enzyme, stabilizes the inactive form  
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Cooperativity   form of allosteric regulation that can amplify enzyme activity  
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Feedback Inhibition   the end product of a metabolic pathway shuts down the pathway  
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