Innate Immunity: Inflammation and Wound Healing
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
|
|
||||
|---|---|---|---|---|---|
| Eosinophils | Defend against parasites; degrade vasoactive substances released by mast cells
🗑
|
||||
| Mast cells | Release chemicals that initiate the inflammatory response (histamine)
🗑
|
||||
| Natural Killer (NK) Cells | Eliminate virus-infected cells
🗑
|
||||
| Macrophages | Phagocytize microorganisms and cellular debris; secrete chemicals that promote tissue healing; activate adaptive immunity
🗑
|
||||
| Neutrophils | Phagocytize microorganisms and cellular debris soon after injury; secrete chemicals that call in longer-acting phagocytes
🗑
|
||||
| Fibrinous exudate | Thick and clotted; indicate more advanced inflammation
🗑
|
||||
| Purulent exudate | also knows as suppurative; containing many white blood cells and indicating bacterial infection (pus)
🗑
|
||||
| Hemorrhagic exudate | Containing many red blood cells indicating bleeding
🗑
|
||||
| Serous exudate | Watery, with few proteins or cells; indicates early inflammation
🗑
|
||||
| Innate immunity | nonspecific first line of defense; physical and biochemical barriers
🗑
|
||||
| Adaptive immunity | also known as acquired immunity is specific, meaning one cell will defend against only one particular antigen
🗑
|
||||
| Complement system | produce biologically active fragments that recruit phagocytes, activate mast cells, and destroy pathogens; activate cascade
🗑
|
||||
| Coagulation (clotting) system | forms a fibrinous meshwork at an injured or inflammed site
🗑
|
||||
| Kinin system | functions to activate and assist inflammatory cells;
🗑
|
||||
| Opsonins | mark antigen for destruction by innate immune cells
🗑
|
||||
| Chemotactic factor | attracts leukocyte to inflammation cite
🗑
|
||||
| Anaphylatoxins | induce mast cell degranulation (C3, C4, C5) produced as part of the activation of complement system
🗑
|
||||
| Classical pathway | activated by proteins of the adaptive immune system (antibodies) bound to their specific targets (antigen)
🗑
|
||||
| Lectin pathway | activated by mannose-containing bacterial carbohydrates (MBL)
🗑
|
||||
| Alternative pathway | activated by gram-negative bacterial and fungal cell wall polysacchrides
🗑
|
||||
| Fibrin | end product of coagulation cascade; protein involved in clotting of the blood
🗑
|
||||
| Bradykinin | an inflammatory mediator that cause dilation of blood vessels, pain, and smooth muscle contraction, an increasing vascular permeability. the primary kinin in its system;
🗑
|
||||
| Cytokines | responsible for activating other cells and regulating inflammatory response
🗑
|
||||
| Chemokines | induce chemotaxis to attract WBCs to cite of infection and promote phagocytosis and wound healing
🗑
|
||||
| Interleukins | produced primarily by macrophages and lymphocytes in response to stimulation of pattern recognition receptors or by other cytokines
🗑
|
||||
| Interferon | protects against viral infection by preventing them from infecting other healthy cell;
🗑
|
||||
| Degranulation | chemical release of the contents of mast cell granules; immediate response
🗑
|
||||
| Synthesis | the new production and release of mediators in response to a stimulus; long term response
🗑
|
||||
| Histamine | vasoactive amine that is produced as part of a local immune response to cause inflammation
🗑
|
||||
| Platelets | also known as thrombocytes; activation lead to interaction with coagulation cascade to stop bleeding
🗑
|
||||
| Neutrophils | predominate in early inflammatory responses (6-10 days after injury);
🗑
|
||||
| Eosinophils | defense against parasites and regulation of vascular mediators
🗑
|
||||
| Basophils | associated with asthma and allergies with same function as mast cells
🗑
|
||||
| Phagocytosis | process by which a cell ingests and disposes of foreign material
🗑
|
||||
| Margination | known as pavementing; adherence of leukocytes to endothelial cells
🗑
|
||||
| Diapedesis | emigration of cells through the endothelial junctions
🗑
|
||||
| Resolution | returning injured tissue to the original structure and function
🗑
|
||||
| Repair | replacement of destroyed tissue with scar tissue
🗑
|
||||
| Scar tissue | composed primarily of collagen to restore the strength of the tissue but not its function
🗑
|
||||
| Primary intention | wounds that heal under conditions of minimal tissue loss
🗑
|
||||
| Secondary intention | wounds that require a great deal more tissue replacement ie. open wound
🗑
|
Review the information in the table. When you are ready to quiz yourself you can hide individual columns or the entire table. Then you can click on the empty cells to reveal the answer. Try to recall what will be displayed before clicking the empty cell.
To hide a column, click on the column name.
To hide the entire table, click on the "Hide All" button.
You may also shuffle the rows of the table by clicking on the "Shuffle" button.
Or sort by any of the columns using the down arrow next to any column heading.
If you know all the data on any row, you can temporarily remove it by tapping the trash can to the right of the row.
To hide a column, click on the column name.
To hide the entire table, click on the "Hide All" button.
You may also shuffle the rows of the table by clicking on the "Shuffle" button.
Or sort by any of the columns using the down arrow next to any column heading.
If you know all the data on any row, you can temporarily remove it by tapping the trash can to the right of the row.
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
Created by:
dpenaga
Popular Nursing sets