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hair, skin, nails

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Term
Definition
acrocyanosis   bluish discoloration of hands and feet - may be present at birth and may persist for several days or longer if newborn is kept in cool ambient environment  
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alopecia   hair loss  
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alopecia areata   sudden, rapid, patchy loss of hair, usually from scalp or face  
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annular   round, active margins with central clearing  
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apocrine glands   specialized structures found only in the axillae, nipples, areolae, anogenital area, eyelids, and external ears  
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cellular stratum   one of the major layers in epidermis - where keratin cells are synthesized  
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cellulitis   diffuse, acute infection of the skin and subcutaneous tissue  
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chloasma   occurs in pregnant women - found on forehead, cheeks, bridge of nose, and chin - blotchy and symmetrical  
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confluent   lesions run together  
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cutis mormorata   mottled appearance of the body and extremities of the skin of newborns when exposed to decreased temperatures  
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dermatomal   lesion that follows a nerve or segment of the body  
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dermis   richly vascular connective tissue layer of the skin that supports and separates the epidermis from the cutaneous adipose tissue  
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ecchymosis   discoloration (bruising) produced by injury  
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eccrine glands   glands that open directly to the skin surface and are found throughout the body except in the lip margins, eardrums, nail beds, inner surface of the prepuce and glans penis  
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exzematous dermatitis   most common inflammatory skin disorder - several forms exist: irritant contact dermatitis, allergic contact dermatitis, and atopic dermatitis  
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epidermis   outer portion of skin - consists of two layers  
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erythema toxicum   pink papular rash with vesicles superimposed on thorax, back, buttocks, and abdomen in newborns about 36 hrs after birth  
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folliculitis   inflammation and infection of the hair follicle and surrounding dermis  
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furnucle   deep seated infection of the pilosebaceous unit  
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generalized   widely distributed or present in several areas simultaneously  
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herpes simplex   infection caused by herpes simplex virus  
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herpes zoster   infection caused by varicella zoster virus  
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hypodermis   layer of skin that connects the dermis to the underlying organs that consist of loose connective tissue filled with fatty cells  
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keloid   irregular shape, elevated, progressively enlarging hypertrophied scar tissue  
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keratin   waterproofing protein found in the stratum corneum  
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lanugo   fine, silky hair of newborns found on back and shoulders  
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melanin   synthesized in the stratum germinativum by melanocytes and is pigment that gives skin its color  
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mongolian spots   irregular areas of deep blue pigmentation on the sacral and gluteal regions of a newborn - most predominately occurs in people of African, Native American, Asian, and Latin descent  
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morbilliform   refers to maculopapular lesions that become confluent on the face and body  
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nails   epidermal cells converted to hard plates of keratin  
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nevus   mole that varies in size and degree of pigmentation  
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papillae   loops of capillaries that supply nourishment for hair follicles  
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petechiae   tiny, flat, purple or red spots on skin surface - resulting from minute hemorrhages within dermal layer smaller than 0.5cm in diameter  
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pityriasis rosea   self-limiting inflammation of unknown cause  
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plaque   type of skin lesion common in pts with psoriasis  
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psoriasis   chronic and recurrent disease of keratin synthesis  
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pruritic urticarial plapules and plaque of pregnancy   benign dermatosis that usually arises late in 3rd trimester of first pregnancy  
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reticulate   referring to lesion with netlike or lacy appearance  
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rosacea   chronic inflammatory skin disorder  
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salmon patches (stork bite)   flat, deep pink localized areas usually seen on mid-forehead, eyelids, upper lip, and back of neck on newborn  
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sebum   lipid substance that keeps skin and hair from drying out  
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serpiginous   lesions that appear to occur in wavy line  
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stellate   star shaped lesion  
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stratum corneum   outermost layer of epidermis - protects body against environmental stressors and water loss  
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stratum lucidum   layer of epidermis found in thicker skin of palms and soles  
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telangiectasis   permanently dilated, small blood vessels consisting of venules, capillaries, or arterioles  
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terminal hair   course, longer, thicker, and usually pigmented hair  
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tinea   group of noncandidal fungal infections that involve the stratum corneum, nails and hair  
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vellus hair   short, fine hair that is non-pigmented  
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vernix caseosa   mixture of sebum and cornified epidermis that covers infant's body at birth  
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vesicle   fluid-filled and elevated, but superficial, skin lesion  
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wood's lamp   type of lamp used to evaluate epidermal hypopigmented or hyperpigmented lesion and to distinguish the fluorescing skin lesions  
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purpura   red-purple nonblanchable discoloration greater than 0.5 cm in diameter  
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spider angioma   red central body with radiating spider-like legs that blanch with pressure to central body  
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venous star   bluish spider, linear or irregularly shaped - does not blanch with pressure  
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clostridium gas gangrene   smells like rotten apples  
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proteus infection   smells mousy  
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pseudomonas infection (especially burns)   smells grapelike  
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tuberculosis lymphadentitis (scrofula)   smells like stale beer  
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anaerobic infection; scurvy   smells putrid  
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intestinal obstruction; peritonitis   smells feculent  
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phenylketonuria   smells mousy, musty  
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skin lesion   describes any pathologic skin change or occurrence - may be primary or secondary  
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primary skin lesion   those that occur as initial spontaneous manifestations of a pathologic process  
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secondary skin lesion   those that result from later evolution of or external trauma to a primary lesion  
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macule   flat, circumscribed area that is a change in the color of the skin - less than 1 cm in diameter - ex) freckles, flat moles, petechiae, measles  
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papule   elevated, firm circumscribed area - less than 1 cm in diameter - ex) wart (verruca), elevated moles, lichen planus  
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patch   flat, nonpalpable, irregularly shaped macule greater than 1 cm in diameter - ex) vitiligo, port wine stains, mongolian spots, cafe au lait patch  
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plaque   elevated, firm, and rough lesion with flat top surface greater than 1 cm in diameter - ex) psoriasis, seborrheic and actinic kerotoses  
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wheal   elevated, irregular shaped area of cutaneous edema - solid, transient, variable diameter - ex) insect bites, urticaria, allergic reaction  
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nodule   elevated, firm, circumscribed lesion - deeper in dermis than a papule - 1-2 cm in diameter - ex) erythema nodosum, lipoma  
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tumor   elevated and solid lesion - may or may not be clearly demarcated - deeper in dermis - greater than 2 cm in diameter - ex) neoplasms, benign tumor, lipoma  
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vesicle   elevated, circumscribed, superficial, not into dermis - filled with serous fluid - less than 1 cm in diameter - ex) varicella (chickenpox), herpes zoster (shingles)  
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bulla   vesicle greater than 1 cm in diameter - ex) blister, pemphigus vulgaris  
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pustule   elevated, superficial lesion - similar to vesicle but filled with purulent fluid - ex) impetigo, acne  
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cyst   elevated, circumscribed encapsulated lesion - in dermis or subcutaneous layer - filled with liquid or semisolid material - ex) sebacceous cyst, cystic acne  
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scale   heaped up, keratinized cells; flaky skin, irregular, thick or thin, dry or oily, variation in size - ex) flaking of skin with seborrheic dermatitis or following drug reaction, dry skin  
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lichenification   rough, thickened epidermis secondary to persistent rubbing, itching, or skin irritation - often involves flexor surface of extremity - ex) chronic dermatitis  
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scar   thin to thick fibrous tissue that replaces normal skin following injury or laceration to the dermis  
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excoriation   loss of epidermis - linear hollowed out, crusted area - ex) abrasion or scratch, scabies  
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fissure   linear crack or break from epidermis to dermis - may be moist or dry - ex) athlete's foot, cracks at corner of mouth  
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erosion   loss of part of the epidermis - depressed, moist, glistening, follows rupture of vesicle or bulla - ex) varicella, variola after rupture  
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ulcer   loss of epidermis and dermis - concave, varies in size - ex) decubiti, stasis ulcer  
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crust   dried serum, blood or purulent exudates - slightly elevated, size varies - brown, red, black, tan or straw-colored - ex) scab on abrasion, eczema  
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atrophy   thinning of skin surface and loss of skin markings - skin translucent and paper-like - ex) striae, aged skin  
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discrete margin   well demarcated or defined - able to draw a line around it with confidence  
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indistinct margin   poorly defined, have borders that merge into normal skin or outlying ill-defined papules  
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active margin   margin of lesion shows greater activity than center  
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irregular margin   nonsmooth or notched margin  
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border raised above margin   center of lesion depressed compared to the edge  
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advancing margin   expanding at margins  
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central clearing   erythematous border surrounds lighter skin  
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desquamation   peeling or sloughing of skin  
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keratotic   hypertrophic stratum corneum  
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punctation   central umbillication or dimpling  
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basal cell carcinoma   most common form of skin cancer - arises from basal layer of epidermis - occurs most frequently on face, ears, neck, scalp, shoulders  
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squamous cell carcinoma   second most common form of skin cancer - malignant tumor arises in epithelium - occurs most frequently in sun exposed areas, scalp, back of hands, lower lip, ear  
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malignant melanoma   lethal form of skin cancer that develops from melanocytes  
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