Morphine
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| GENERIC NAME | Morphine Sulfate
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| BRAND NAME | Astramorph/pf
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| CLASS | Opioid analgesic (schedule II narcotic)
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| MECHANISM OF ACTION | Alleviates pain through CNS action, Suppresses fear and anxiety centers in brain, depresses brain stem respiratory centers, increases peripheral venous capacitance and decreases venous return, decreases preload, after load, & myocardial oxygen demand.
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| INDICATIONS | Severe CHF, pulmonary edema, chest pain associated with acute MI, analgesia for moderate to severe acute and chronic pain (use with caution)
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| CONTRAINDICATIONS | Head injury, exacerbated COPD, depressed respiratory drive, hypotension, undiagnosed abdominal pain, decreased LOC, suspected hypovolemia, patients who have taken MAOIs within the past 14 days.
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| ADVERSE REACTIONS | Respiratory depression, hypotension, decreased LOC, nausea, vomiting, Bradycardia, tachycardia, syncope, facial flushing, euphoria, bronchospasm, dry mouth.
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| NOTES ON ADMINISTRATION | Pregnancy Category C. Morphine rapidly crosses the placenta. Safety in neonate not established. Use with caution in geriatric population COPD, & asthma. Vagotonic effect in patient with acute inferior MI (Bradycardia, heart block).
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| INCOMPATABILITIES/DRUG INTERACTIONS | Potentiates sedative effects of phenothiazines. CNS depressant may potentiate effects of morphine. MAOIs may cause paradoxical excitation.
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| DOSE/ROUTE, Adult | Initial dose
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| DOSE/ROUTE Pediatric | .1-.2 mg/kg per dose via IV. IO. IM, or SC; Maximum dose of 5mg.
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| ONSET OF ACTION | Immediate
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| PEAK EFFECTS | 20 minutes
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| DURATION OF ACTION | 2-7 hours
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| AZ DRUG BOX SUPPLY RANGE | 20mg
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Created by:
klindley
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