Verapamil
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| GENERIC NAME | Verapamil
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| BRAND NAME | Isoptin
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| CLASS | Antiarrhythmic
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| MECHANISM OF ACTION | Calcium channel blocker. Class IV antiarrhythmic, prolongs av nodal refractory period, dilates coronary arteries, and arterioles.
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| INDICATIONS | PSVT, PAT, Atrial fibrillation and atrial flutter with rapid ventricular response
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| CONTRAINDICATIONS | WPW syndrome, 2nd or 3rd degree AV block, sick sinus syndrome (unless pt. has functioning pacemaker), hypotension, Cardiogenic shock, severe CHF, pulmonary edema, pt receiving IV beta blocker, wide complex tachycardia, children less then 12months of age.
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| ADVERSE REACTIONS | Hypotension, AV block, Bradycardia, Asystole, dizziness, HA, N/V, Complete AV block, peripheral edema.
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| NOTES ON ADMINISTRATION | Pregnancy category C. be prepared for Asystole and resuscitation efforts.
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| INCOMPATABILITIES/DRUG INTERACTIONS | Increases serum concentration of digoxin. Beta adrenergic blockers may have additive negative inotropic and chronotropic effects. Antihypertensives may potentiate Hypotensive effects.
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| DOSE/ROUTE | Adult
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| Pediatric | 0.1-0.2 mg/kg/dose IV, IO push over 2 minutes. Repeat dose in 30 minutes if not effective. Don’t use in children <12 months
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| ONSET OF ACTION | 2-5 minutes
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| PEAK EFFECTS | Variable
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| DURATION OF ACTION | 30-60 minutes
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| AZ DRUG BOX SUPPLY RANGE | ??
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Created by:
klindley
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