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Verapamil

QuestionAnswer
GENERIC NAME Verapamil
BRAND NAME Isoptin
CLASS Antiarrhythmic
MECHANISM OF ACTION Calcium channel blocker. Class IV antiarrhythmic, prolongs av nodal refractory period, dilates coronary arteries, and arterioles.
INDICATIONS PSVT, PAT, Atrial fibrillation and atrial flutter with rapid ventricular response
CONTRAINDICATIONS WPW syndrome, 2nd or 3rd degree AV block, sick sinus syndrome (unless pt. has functioning pacemaker), hypotension, Cardiogenic shock, severe CHF, pulmonary edema, pt receiving IV beta blocker, wide complex tachycardia, children less then 12months of age.
ADVERSE REACTIONS Hypotension, AV block, Bradycardia, Asystole, dizziness, HA, N/V, Complete AV block, peripheral edema.
NOTES ON ADMINISTRATION Pregnancy category C. be prepared for Asystole and resuscitation efforts.
INCOMPATABILITIES/DRUG INTERACTIONS Increases serum concentration of digoxin. Beta adrenergic blockers may have additive negative inotropic and chronotropic effects. Antihypertensives may potentiate Hypotensive effects.
DOSE/ROUTE Adult
Pediatric 0.1-0.2 mg/kg/dose IV, IO push over 2 minutes. Repeat dose in 30 minutes if not effective. Don’t use in children <12 months
ONSET OF ACTION 2-5 minutes
PEAK EFFECTS Variable
DURATION OF ACTION 30-60 minutes
AZ DRUG BOX SUPPLY RANGE ??
Created by: klindley