thiamine
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GENERIC NAME | None
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BRAND NAME | Thiamine
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CLASS | Vitamin B1
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MECHANISM OF ACTION | Combines with ATP to form thiamine pyrophosphate coenzyme, a necessary component for carbohydrate metabolism. The brain is extremely sensitive to thiamine deficiency.
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INDICATIONS | Coma of unknown origin, delirium tremens, beriberi, Wernicke’s encephalopathy.
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CONTRAINDICATIONS | None
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ADVERSE REACTIONS | Hypotension from to rapid of an injection or to high of a dose, anxiety, diaphoresis, N/V or hypersensitivity.
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NOTES ON ADMINISTRATION | Pregnancy category A. Large IV doses may cause respiratory difficulties. Anaphylaxis reactions reported.
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INCOMPATABILITIES/DRUG INTERACTIONS | Give thiamine before glucose under all circumstances.
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DOSE/ROUTE | Adult
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Pediatric | 10-25mg slow IV, or IM
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ONSET OF ACTION | Rapid
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PEAK EFFECTS | Variable
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DURATION OF ACTION | Dependent upon degree of deficiency
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AZ DRUG BOX SUPPLY RANGE | 100mg
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Created by:
klindley
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