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thiamine

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Question
Answer
GENERIC NAME   None  
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BRAND NAME   Thiamine  
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CLASS   Vitamin B1  
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MECHANISM OF ACTION   Combines with ATP to form thiamine pyrophosphate coenzyme, a necessary component for carbohydrate metabolism. The brain is extremely sensitive to thiamine deficiency.  
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INDICATIONS   Coma of unknown origin, delirium tremens, beriberi, Wernicke’s encephalopathy.  
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CONTRAINDICATIONS   None  
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ADVERSE REACTIONS   Hypotension from to rapid of an injection or to high of a dose, anxiety, diaphoresis, N/V or hypersensitivity.  
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NOTES ON ADMINISTRATION   Pregnancy category A. Large IV doses may cause respiratory difficulties. Anaphylaxis reactions reported.  
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INCOMPATABILITIES/DRUG INTERACTIONS   Give thiamine before glucose under all circumstances.  
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DOSE/ROUTE   Adult  
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Pediatric   10-25mg slow IV, or IM  
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ONSET OF ACTION   Rapid  
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PEAK EFFECTS   Variable  
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DURATION OF ACTION   Dependent upon degree of deficiency  
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AZ DRUG BOX SUPPLY RANGE   100mg  
🗑


   

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Created by: klindley
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