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Albuterol

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Answer
GENERIC NAME   Albuterol  
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BRAND NAME   Proventil, ventolin  
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CLASS   Sympathomimetic, bronchodilator  
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MECHANISM OF ACTION   Selective beta 2 agonist that stimulates adrenergic receptors of the Sympathomimetic nervous system resulting in smooth muscle relaxation in the bronchial tree and peripheral vasculature.  
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INDICATIONS   Treatment of bronchospasm in patients with reversible obstructive airway disease (COPD, Asthma). Prevention of exercise induced bronchospasm.  
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CONTRAINDICATIONS   Known prior hypersensitivity reactions. Tachycardia, arrhythmias especially those caused by digitalis. Synergistic with other sympathomimetics.  
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ADVERSE REACTIONS   Often dose related and include restlessness, tremors, dizziness, palpitations, tachycardia, nervousness, peripheral vasodilation, nausea, vomiting, hyperglycemia, increased BP, and paradoxical bronchospasm.  
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NOTES ON ADMINISTRATION   Pregnancy safety category C. antagonized by beta blockers. May precipitate angina and arrhythmias. Should only be administered via inhalation in prehospital setting.  
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INCOMPATABILITIES/DRUG INTERACTIONS   Tricyclic antidepressants may potentiate vasculature effects. Beta blockers are antagonistic. May potentiate Hypokalemia caused by diuretics.  
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DOSE/ROUTE Adult   2.5mg. Over 10-15 minutes. MDI 1-2 inhalations with 5 minutes in between.  
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DOSE/ROUTE Pediatric   administer solution of 0.05-0.15 mg/kg/dose. May repeat every 20 min. up to 3 doses.  
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ONSET OF ACTION   5-15min.  
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PEAK EFFECTS   30min-2hours  
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DURATION OF ACTION   3-4 hours.  
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AZ DRUG BOX SUPPLY RANGE   10mg  
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Created by: klindley
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