Albuterol
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GENERIC NAME | Albuterol
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BRAND NAME | Proventil, ventolin
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CLASS | Sympathomimetic, bronchodilator
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MECHANISM OF ACTION | Selective beta 2 agonist that stimulates adrenergic receptors of the Sympathomimetic nervous system resulting in smooth muscle relaxation in the bronchial tree and peripheral vasculature.
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INDICATIONS | Treatment of bronchospasm in patients with reversible obstructive airway disease (COPD, Asthma). Prevention of exercise induced bronchospasm.
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CONTRAINDICATIONS | Known prior hypersensitivity reactions. Tachycardia, arrhythmias especially those caused by digitalis. Synergistic with other sympathomimetics.
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ADVERSE REACTIONS | Often dose related and include restlessness, tremors, dizziness, palpitations, tachycardia, nervousness, peripheral vasodilation, nausea, vomiting, hyperglycemia, increased BP, and paradoxical bronchospasm.
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NOTES ON ADMINISTRATION | Pregnancy safety category C. antagonized by beta blockers. May precipitate angina and arrhythmias. Should only be administered via inhalation in prehospital setting.
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INCOMPATABILITIES/DRUG INTERACTIONS | Tricyclic antidepressants may potentiate vasculature effects. Beta blockers are antagonistic. May potentiate Hypokalemia caused by diuretics.
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DOSE/ROUTE Adult | 2.5mg. Over 10-15 minutes. MDI 1-2 inhalations with 5 minutes in between.
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DOSE/ROUTE Pediatric | administer solution of 0.05-0.15 mg/kg/dose. May repeat every 20 min. up to 3 doses.
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ONSET OF ACTION | 5-15min.
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PEAK EFFECTS | 30min-2hours
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DURATION OF ACTION | 3-4 hours.
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AZ DRUG BOX SUPPLY RANGE | 10mg
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Created by:
klindley
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