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Albuterol
| Question | Answer |
|---|---|
| GENERIC NAME | Albuterol |
| BRAND NAME | Proventil, ventolin |
| CLASS | Sympathomimetic, bronchodilator |
| MECHANISM OF ACTION | Selective beta 2 agonist that stimulates adrenergic receptors of the Sympathomimetic nervous system resulting in smooth muscle relaxation in the bronchial tree and peripheral vasculature. |
| INDICATIONS | Treatment of bronchospasm in patients with reversible obstructive airway disease (COPD, Asthma). Prevention of exercise induced bronchospasm. |
| CONTRAINDICATIONS | Known prior hypersensitivity reactions. Tachycardia, arrhythmias especially those caused by digitalis. Synergistic with other sympathomimetics. |
| ADVERSE REACTIONS | Often dose related and include restlessness, tremors, dizziness, palpitations, tachycardia, nervousness, peripheral vasodilation, nausea, vomiting, hyperglycemia, increased BP, and paradoxical bronchospasm. |
| NOTES ON ADMINISTRATION | Pregnancy safety category C. antagonized by beta blockers. May precipitate angina and arrhythmias. Should only be administered via inhalation in prehospital setting. |
| INCOMPATABILITIES/DRUG INTERACTIONS | Tricyclic antidepressants may potentiate vasculature effects. Beta blockers are antagonistic. May potentiate Hypokalemia caused by diuretics. |
| DOSE/ROUTE Adult | 2.5mg. Over 10-15 minutes. MDI 1-2 inhalations with 5 minutes in between. |
| DOSE/ROUTE Pediatric | administer solution of 0.05-0.15 mg/kg/dose. May repeat every 20 min. up to 3 doses. |
| ONSET OF ACTION | 5-15min. |
| PEAK EFFECTS | 30min-2hours |
| DURATION OF ACTION | 3-4 hours. |
| AZ DRUG BOX SUPPLY RANGE | 10mg |