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Albuterol

QuestionAnswer
GENERIC NAME Albuterol
BRAND NAME Proventil, ventolin
CLASS Sympathomimetic, bronchodilator
MECHANISM OF ACTION Selective beta 2 agonist that stimulates adrenergic receptors of the Sympathomimetic nervous system resulting in smooth muscle relaxation in the bronchial tree and peripheral vasculature.
INDICATIONS Treatment of bronchospasm in patients with reversible obstructive airway disease (COPD, Asthma). Prevention of exercise induced bronchospasm.
CONTRAINDICATIONS Known prior hypersensitivity reactions. Tachycardia, arrhythmias especially those caused by digitalis. Synergistic with other sympathomimetics.
ADVERSE REACTIONS Often dose related and include restlessness, tremors, dizziness, palpitations, tachycardia, nervousness, peripheral vasodilation, nausea, vomiting, hyperglycemia, increased BP, and paradoxical bronchospasm.
NOTES ON ADMINISTRATION Pregnancy safety category C. antagonized by beta blockers. May precipitate angina and arrhythmias. Should only be administered via inhalation in prehospital setting.
INCOMPATABILITIES/DRUG INTERACTIONS Tricyclic antidepressants may potentiate vasculature effects. Beta blockers are antagonistic. May potentiate Hypokalemia caused by diuretics.
DOSE/ROUTE Adult 2.5mg. Over 10-15 minutes. MDI 1-2 inhalations with 5 minutes in between.
DOSE/ROUTE Pediatric administer solution of 0.05-0.15 mg/kg/dose. May repeat every 20 min. up to 3 doses.
ONSET OF ACTION 5-15min.
PEAK EFFECTS 30min-2hours
DURATION OF ACTION 3-4 hours.
AZ DRUG BOX SUPPLY RANGE 10mg
Created by: klindley