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Chapter 14

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Red Blood Cells   Are relatively large microscopic cells without nuclei. They transport oxygen from the lungs to all of the living tissues of the body, and carry away carbon dioxide.  
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White Blood Cells   Make up a very small part of blood volume, most are produced in bone marrow. They attack bacteria, viruses, and fungi.  
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Platelets   Are cell fragments without nuclei that work with blood clotting chemicals at the site of wounds. Individual platelets are about 1/3 the size of red cells.  
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Plasma   Is the relatively clear, yellow tinted water, sugar, fat, protein and salt solution which carries the red cells, white cells, and platelets.  
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Erythrocytes   Are red blood cells, formed elements.  
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Bioconcave   Lacks nuclei and mitochondria filled with hemoglobin. Enables RBC's to form stacks that flow through narrow blood vessels. Enables RBC's to flex, using spectrin protein.  
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Erythropoietin   Hormone that controls the production of erythrocytes. Erythrocytes are made via hypoxia.  
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Hematopoiesis   Blood formation, occurs in the red bone, starts with hemocystoblast. Begins with hemocystoblast then reticulocytes and finally erythrocytes.  
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Hemoglobins   Oxygen-carrying; each RBC is about 1/3 hemoglobin by volume. When hemoglobin combines with oxygen, the resulting oxyhemoglobin is bright red. When the oxygen is released, the resulting deoxyhemoglobin is darker.  
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Composition of Hemoglobin   4 globular protein subunits, each composed of a protein chain tightly associated with a non-protein heme group.  
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Function of Hemoglobin   Carries oxygen from the lungs to the tissues of the body; helps in transportation of carbon dioxide and hydrogen ions back into the lungs.  
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Neutrophils   Fights infection  
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Eosinophils   Fights off worms and allergic reactions.  
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Basophils   Release heparin and histamine.  
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Monocytes   Phagocytize bacteria, dead cells and other in tissue.  
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Lymphocytes   Attack microorganisms, tumor cells, and transplanted cells.  
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Plasma   Clear, straw-colored liquid part of the blood in which cells and platelets are suspended. 92% water; contains a complex mixture of organic and inorganic molecules biochemicals including amino acids, nucleic acids, carbohydrates and a variety of lipids.  
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Functions of Plasma   Carrying nutrients, gases hormones, vitamins; regulate fluid and electrolyte balance; maintaining a favorable pH.  
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Plasma Proteins   Most abundant dissolved solute - albumins: help maintain colloid osmotic pressure. Globulin: Alpha-beta-transport lipids and vitamins; gamma-constitute the antibodies of immunity; Fibrinogen: Plays a key role in blood coagulation.  
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Blood Gases   Oxygen and carbon dioxide  
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Plasma Nutrients   Amino acids, simple sugars, nucleotides and lipids absorbed from digestive tract.  
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Non-proteins Nitrogenous Substance (NPNs)   Group includes amino acids, urea, uric acid, creatine, and creatinine.  
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Electrolytes   Absorbed from the intestine or released as by-products of cellular metabolism. Include sodium, potassium, calcium, magnesium, chloride, bicarbonate phosphate and sulfate ions. Important in maintaining osmotic pressure and pH of plasma.  
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