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Dexamethasone sodium phosphate

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Question
Answer
GENERIC NAME   Dexamethasone sodium phosphate  
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BRAND NAME   Decadron, Hexadrol  
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CLASS   Corticosteroid  
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MECHANISM OF ACTION   Suppresses acute and chronic inflammation. Immunosuppressive effects.  
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INDICATIONS   Anaphylaxis, spinal cord injury, asthma, croup, elevated ICP, as an adjunct to treatment for shock.  
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CONTRAINDICATIONS   Hypersensitivity  
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ADVERSE REACTIONS   HTN, Sodium and water retention, GI bleeding, TB. None from a single dose.  
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NOTES ON ADMINISTRATION   Pregnancy safety unknown. Protect from heat. Toxicity and side effects with long term use.  
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INCOMPATABILITIES/DRUG INTERACTIONS   Calcium, Metaraminol.  
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DOSE/ROUTE Adult   10-100mg IV (1mg/kg slow IV bolus)  
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DOSE/ROUTE Pediatric   0.25-1mg/kg/dose IV, IO, IM  
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ONSET OF ACTION   Hours  
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PEAK EFFECTS   8-12 hours  
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DURATION OF ACTION   24-72 hours.  
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AZ DRUG BOX SUPPLY RANGE   8mg optional  
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Created by: klindley
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