Calcium Chloride
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| GENERIC NAME | None
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| BRAND NAME | Calcium Chloride
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| CLASS | Electrolyte
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| MECHANISM OF ACTION | Increases cardiac contractile state (positive inotropic effect), May enhance ventricular automaticity
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| INDICATIONS | 1. Hypoglycemia, 2. Hyperkalemia 3. Magnesium sulfate overdose 4. Calcium channel blocker overdose 5. Adjunctive therapy in treatment of insect bites and stings
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| CONTRAINDICATIONS | 1. Hypercalcemia 2. V-fib 3. Digitalis toxicity
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| ADVERSE REACTIONS | 1. Bradycardia, 2. Asystole. 3. Hypotension 4.Peripheral Vasodilation. 5. Metallic taste. 6. Local necrosis. 7. Coronary and cerebral artery spasm. 8. Nausea and Vomiting.
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| NOTES ON ADMINISTRATION | Pregnancy safety Category C. Do not use routinely in cardiac arrest.
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| INCOMPATABILITIES/DRUG INTERACTIONS | May worsen arrhythmias secondary to digitalis toxicity. May antagonize the effects of verapamil. Do not mix with or infuse immediately before or after sodium bicarbonate without intervening flush.
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| DOSE/ROUTE Adult | 500-1000mg (5-10 ml of a 10% solution) IV/IO push for Hyperkalemia and calcium channel blocker overdose. May be repeated as needed. DOSE/ROUTE Pediatric
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| ONSET OF ACTION | 5-15 minutes
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| PEAK EFFECTS | 3-5 minutes.
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| DURATION OF ACTION | 15-30 minutes, but may persist for 4 hours (dose dependent).
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| AZ DRUG BOX SUPPLY RANGE | 1 Gram
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