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Calcium Chloride

BRAND NAME Calcium Chloride
CLASS Electrolyte
MECHANISM OF ACTION Increases cardiac contractile state (positive inotropic effect), May enhance ventricular automaticity
INDICATIONS 1. Hypoglycemia, 2. Hyperkalemia 3. Magnesium sulfate overdose 4. Calcium channel blocker overdose 5. Adjunctive therapy in treatment of insect bites and stings
CONTRAINDICATIONS 1. Hypercalcemia 2. V-fib 3. Digitalis toxicity
ADVERSE REACTIONS 1. Bradycardia, 2. Asystole. 3. Hypotension 4.Peripheral Vasodilation. 5. Metallic taste. 6. Local necrosis. 7. Coronary and cerebral artery spasm. 8. Nausea and Vomiting.
NOTES ON ADMINISTRATION Pregnancy safety Category C. Do not use routinely in cardiac arrest.
INCOMPATABILITIES/DRUG INTERACTIONS May worsen arrhythmias secondary to digitalis toxicity. May antagonize the effects of verapamil. Do not mix with or infuse immediately before or after sodium bicarbonate without intervening flush.
DOSE/ROUTE Adult 500-1000mg (5-10 ml of a 10% solution) IV/IO push for Hyperkalemia and calcium channel blocker overdose. May be repeated as needed. DOSE/ROUTE Pediatric
ONSET OF ACTION 5-15 minutes
PEAK EFFECTS 3-5 minutes.
DURATION OF ACTION 15-30 minutes, but may persist for 4 hours (dose dependent).
Created by: klindley