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AP Bio Chapter 9

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Term
Definition
Anti parallel   Pertaining to molecular orientation in which a molecule to parts of a molecule have opposing directions.  
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Bacteriophage   Any of a group of viruses that infect bacteria.  
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Base Pair   In double-stranded DNA, a pair of nucleotides formed by the complementary base pairing of a purine on one strand and a pyrimidine on the other.  
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Deoxyribonucleotide Triphosphate   The raw materials for DNA synthesis: deoxyadenosine triphosphate (dATP), deoxythymidine triphosphate (dTTP), deoxycytidine triphosphate (dCTP), and deoxyguanosine triphosphate (dGTP).  
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DNA ligase   Enzyme that unites broken DNA strands during replication and recombination.  
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DNA polymerase   Any of a group of enzymes that catalyze the formation of DNA strands from a DNA template.  
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helical   Shaped like a screw or spring; occurs in DNA and proteins.  
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Lagging strand   In DNA replication, the daughter strand that is synthesized in discontinuous stretches.  
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Leading Strand   In DNA replication, the daughter strand that is synthesized continuously.  
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Okazaki Fragments   Newly formed DNA making up the lagging strand in DNA replication.  
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Origin of Replication   DNA sequence at which helicase unwinds the DNA double helix and DNA polymerase binds to initiate DNA replication.  
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Polymerase Chain Reaction (PCR)   An enzymatic technique for the rapid production of millions of copies of a particular stretch of DNA where only a small amount of the parent molecule is available.  
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Primase   An enzyme that catalyzes the synthesis of a primer for DNA replication.  
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Primer   Strand of nucleic acid, usually RNA, that is the necessary starting material for the synthesis of a new DNA strand, which is synthesized from the 3' end of the primer.  
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Processive   Pertaining to an enzyme that catalyzes many reactions each time it binds to a substrate, as DNA polymerase does during DNA replication.  
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Replication Fork   A point at which a DNA molecule is replicating.  
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Semiconservative Replication   Replication The way in which DNA is synthesized. Each of the two partner strands in a double helix acts as a template for a new partner strand.  
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Template   A molecule or surface on which another molecule is synthesized in complementary fashion, as in the replication of DNA.  
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Transformation   A mechanism for transfer of genetic information in bacteria in which pure DNA from a bacterium of one genotype is taken through the cell surface of a bacterium of a different genotype and incorporated into the chromosome of the recipient cell.  
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Transgenic   Containing recombinant DNA incorporated into the genetic material.  
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Somatic Mutation   Permanent genetic change in a somatic cell. These mutations affect the individual only; they are not passed on to offspring  
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Mutation   A change in the genetic material not caused by recombination  
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Germ Line Mutation   produces gametes  
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Exons   A portion of a DNA molecule, in eukaryotes, that codes for part of a polypeptide  
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Introns   Portion of a gene within the coding region that is transcribed into pre-mRNA but is spliced out prior to translation  
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Silent Mutation   A change in a gene's sequence that has no effect on the amino acid sequence of a protein because it occurs in noncoding DNA or because it does not change the amino acid specified by the corresponding codon.  
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Point Mutation   A mutation that results from the gain, loss, or substitution of a single nucleotide  
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Mutagen   Any agent that increases the mutation rate  
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Deletion   mutation resulting form the loss of a continuous segment of a gene or chromosome. almost never revert to wild type  
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Duplication   mutation in which a segment of a chromosome is duplicated, often by the attachment of a segment lost from its homolog  
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Inversion   rare 180 degree reversal of the order of genes within a segment of a chromosome  
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Translocation   rare mutation event that moves a portion of a new chromosome to a new location, generally on a non homologous chromosome  
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