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Introduction to Cells

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Term
Definition
Magnification Calculation (S1)   Image/Actual  
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Cm (S1)   1 * 10^-2  
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Mm (S1)   1 * 10^-3  
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Un (S1)   1 * 10^-6  
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Nm (S1)   1 * 10^-9  
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Robert Hooke (U1)   First to coin cell (1655) (Cork tree)  
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Anton Van Leevwehoek (U1)   First observation of living cells (1674)  
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Cell theory (3 points) (U1)   1) All living things are made of one or more cell 2) All cells come from pre-existing cells 3) The cell is the smallest unit of life  
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Cell theory exception (U1)   First life on earth  
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Functions of life (7) (U2)   Nutrition Metabolism Growth Response Excretion Homoeostasis Reproduction  
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Paramecium + Chlorella (A2)   N/A  
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Exceptions of cell theory (3) (A1)   Skeletal Muscle Fungal Hyphae Giant Algae  
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Skeletal muscle (A1)   Have cells with a single membrane but multiple nuclei  
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Fungal Hyphae (A1)   Have cells with a single membrane but multiple nuclei  
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Giant Algae (A1)   Cells have a single nucleus but are gigantic and have 3 complex and distinct anatomical parts  
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SA/volume ratio (U3)   --SA of a membrane must be large enough to absorb nutrients, oxygen,other needed substances and to excrete waste products. --Need for nutrients and waste produced is determined by cell volume. --Small cells have larger SA/volume ratio than larger cells  
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Emergent Properties (U4)   --Arise from the interaction of component parts - completely unpredictable --Cells interact to produce a tissue/organ/organism that can do things none of the individual cells could do. -- Eg. Individual brain neurons- full brain  
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Specialized tissues and differentiation (U5 + U6)   --Every somatic (body) cell has the same genes and could develop in any way --Depending on position of each cell and cell to cell signalling such as with hormones, particular genes are switched on adn others are switched off  
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Specialized tissues and differentiation (U5 + U6) - Continued   -- This determines development of the cells -- A group of these differentiated cells becomes a tissue  
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Stem cells (U7)   -- Stem cells are undifferentiated (no function) -- They retain capacity to divide and have ability to differentiate along different paths into all types of cells (pluripotent/totipotent)  
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Where are stem cells derived from? (A3)   -- Human embryos -- Leftover from IVF -- From the placenta -- The umbilical cord -- Adult tissue  
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Steps of stem cell work (A3)   -- Desired type of stem cell is identified, extracted and grown -- Then placed in biochemical solution that will cause cells to differentiate into desired type -- Then implanted into patient's own tissues so they function with the body's natural cells  
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Stem cells - Stargardts (A3)   -- New technologies rely on replacing diseased/dysfunctional cells with healthy/functioning ones -- Embryotic stem cells are isolated and injected into retina -- Cells differentiate into retinal cells -- Treatment is in clinical trials  
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Stem cells - Leukemia (A3)   -- Bone marrow cancer -- Lots of non-functioning white blood cells --Treatment: Remove marrow (marrow produces blood-cells) -- Lost cells must be replaced  
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Stem cells - Leukemia (A3) Continued   -- Haematopoetic stem cells are harvested from a healthy person's bone marrow -- Cells then used to replace cancerous bone marrow after chemo destroys cancerous tissues.  
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Ethics of stem cells - Pros (A4)   Some diseases (like stargardts) have no other means of treatment -- Outcome of other diseases ( like Leukemia) are largely improved  
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Ethics of stem cells - Cons (A4)   --Specially created embryos: Religious and moral objection to detroying human embryos -- Umbilical cords:Playing god - it's unnatural -- Adult tissues: Research is very expensive and money may be spent in better ways -- All apply to above  
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