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Local Anesthetic Agents Quizzes

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Question
Answer
In the depolarized nerve cell, there are more positively charged ions outside the cell than inside because the nerve membrane is relatively impermeable to sodium.   False  
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The minimal threshold stimulus required to excite a C-fiber will also be sufficient to stimulate an A-fiber.   False  
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The physioanatomical process that transmits pain from the free nerve endings to the central nervous system (CNS) is:   Pain perception  
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When energy for conduction is derived from the nerve cell membrane itself and is no longer dependent on the stimulus for continuance, the conduction is considered to be:   Self-propagating  
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The relative refractory period occurs during the fraction of a millisecond when a nerve fiber can be excited only by a much stronger stimulus than the initial stimulus.   True  
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Nerve fibers are divided according to size and conduction velocity or speed. The two fibers we are concerned with in dentistry are:   A-delta and C  
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Nerve conduction along a myelinated nerve expends more energy due to increased speed and intensity.   False  
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The absolute refractory period occurs during the fraction of a millisecond when a nerve fiber can be exited only by a much stronger stimulus than the initial stimulus.   False  
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The larger the diameter the nerve fiber, the more likely that fiber is to be myelinated.   True  
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Saltatory conduction refers to:   Rapid transmission of nerve impulses along a myelinated nerve fiber.  
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A group of nerve fibers bundled together is referred to as:   Nerve trunk  
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A group of cell bodies (nerve) bundled together are referred to as:   A ganglion  
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Assume for a moment that all nerve fibers affected in an area are the same size. The difference in pain intensity is derived form:   The number of individual cells excited and the frequency of excitation (duration of stimulus)  
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When a stimulus of sufficient intensity to create an impulse is applied to a nerve ending, the permeability of the cell membrane is altered and depolarization is initiated. What does not happen during depolarization?   Sodium is pumped out of the nerve cell by the sodium pump  
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In myelinated nerves, local anesthetics must diffuse through the myelin sheath to reach the nerve membrane to block the nerve impulse.   False  
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Saltatory conduction is a term that refers to:   Impulse conduction which leaps form node to node and impulse conduction in myelinated nerves.  
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When a nerve is at rest, which of the following statements is true?   The cell membrane can be excited if a stimulus is intense enough to initiate an impulse.  
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Your first patient of the morning stayed up all night studying for his 1:00 history exam. He will most likely have a higher pain reaction threshold than usual.   False  
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As you prepare to anesthetize him, your patient clenched his hands and beads of perspiration form on his upper lip and brow. He is echibiting:   Pain reaction  
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The administration of local anesthesia to control pain is an example of:   Interrupting pain perception  
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Juanita Rodriquez, from Guadalajara, will most likely have a higher pain reaction threshold than Sue Smith, who was raised in Fairbanks, Alaska.   False  
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The most similarity of nerve membrane electrochemical potential exists between:   Polarization and repolarization  
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The resting potential of a nerve fiber is:   Maintained in part by the sodium pump, maintained in part by the permeability of the cell membrane, and an electrochemical gradient of -70 to -90 mV  
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Psychogenic pain may be most accurately described as:   Discomfort for which no organic cause can be determined.  
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Referred pain may be expressed in some part of the body other than its physiological point of origin.   True  
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Which of the following factors significantly improves the effectiveness of a local anesthetic agent?   Protein-binding capability of local anesthetic agent and lipid solubility of local anesthetic agent  
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What are the base molecules responsible for in local anesthetics?   Diffusion of local anesthesia through the nerve membrane, onset time of local anesthesia.  
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What are the cation molecules responsible for in local anesthetics?   Binding at the receptor sites in the ion channels and reduction or prevention of sodium ions through the nerve membrane.  
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Which of the following circumstances would cause the greatest decrease in pH and therefore reduce effectiveness of local anesthetic?   Inflamed tissue using local anesthesia with epinephrine and inflamed tissue using local anesthesia with levonordefrin.  
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Mepivacaine has the lowest pKa of most local anesthetics. This would indicate which of the following?   The local anesthetic has a high percentage of base molecules  
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Which of the following anesthetic/ anesthetics are available in the US with 1:200,000 epinephrine?   Prilocaine and Bupivacaine  
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