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2

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Term
Definition
Alternative Splicing   a regulated process during gene expression that results in a single gene coding for multiple proteins  
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Arachiodonic acid   a fatty acid and a precursor that is metabolized by various enzymes to a wide range of biologically and clinically important eicosanoids involved in cellular signaling  
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Arrestins   Proteins that bind to a receptor to block further signaling; they target receptors for internalization; they redirect signaling to alternative pathways  
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Autophosphrylation   a process by which kinase proteins phosphorylate themselves enzymatically  
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Calthrin   a plasma membrane surface protein that plays a major role in endocytosis of vesicles and internalization of receptors  
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Coactivators   proteins that stimulate gen expression by binding to a transcription factor that has attached to a DNA  
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Cytokines   small proteins produced by cells of the immune system that act as hormones and affect communications between body cells  
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G-protein   cell membrane proteins that are attached to cell surface receptors and upon stimulation of the receptor by a signaling molecule bind to GTP to form an active complex which mediates an intracellular event  
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G-protein coupled kinases   a family of proteins that regulate the activity of G protein-coupled receptors (GPCRs) by phosphorylating specific amino acids to prevent reactivation of the signaling pathway  
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Globulins   a family of proteins in blood that are produced in the liver and can act as carriers of hormones  
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Half life of a hormone   the amount of time it takes for a hormone concentration in blood to be reduced by half of its original concentration  
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Homodimers   a molecule composed of paired identical proteins  
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Hypophysis   another word for the pituitary gland (anterior pituitary = adenohypophysis; posterior pituitary = neurohypophysis)  
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Hypothalamo-pituitary axis   hypothalamus together with the pituitary gland  
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Iodothyronines   any of the iodinated derivatives of thyroid hormones  
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Regulatory System   any stimulus-response mechanism to allow organisms to sense and respond to changes in many different environmental conditions  
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Transcortin   an alpha-globulin that binds and transports biologically active cortisol hormone in plasma  
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Transcription factors   proteins that control which genes are turned on and off in the genome, binds to specific DNA sequence controlling the transcription of DNA to mRNA  
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Transduction   the process of converting a signal into another form  
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Tyrosine kinases   an enzyme that can transfer a phosphate group from ATP to a protein in a cell  
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