General Q's of SCRN
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show | Medial portion of the frontal and parietal lobes ("mohawk"); corpus callosum
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What areas does the MCA feed? (i.e. lobes and/or structures) | show 🗑
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What areas does the PCA feed?(i.e. lobes and/or structures) | show 🗑
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What are the major S/S of MCA stroke? | show 🗑
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show | Contralateral motor deficits (some/few sensory), Foot & leg weaker than arm, face and tongue usually spared, abulia (decreased activity and speech), emotionally labile
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What are the major S/S of PCA stroke? | show 🗑
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show | Hemiparesthesia, followed by isolated hemisensory deficit in face, arm, & leg, may include trunk, pain may develop resistant to treatment; can also have abnormal movements (inability to stand or walk--thalamic astasia); hyper-reflexive tendons, babinski
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What are the major S/S of basal ganglia strokes? | show 🗑
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show | Only if history of CAD, especially if they have stents
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show | 2.5
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What is the target LDL after stroke? (Which would indicate initiation of statin therapy) | show 🗑
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What is the target blood pressure AFTER stroke or TIA (secondary prevention)? | show 🗑
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show | Cranial nerves 9-12
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show | Cranial nerves 3-4
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What crania nerves originate from the pons? | show 🗑
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What are the S/S of carotid dissection? | show 🗑
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show | Nerve tract for the motor cortex
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show | Nearly ALL sensory pathways coming from the cerebral cortex
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show | Hyper-somnolence
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show | BODY TEMPERATURE ;
also (but less prolific), affect circadian rhythm and body H20/osmo
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What is Broca's aphasia? | show 🗑
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Where is Broca's area located? | show 🗑
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What is Werneckies aphasia? | show 🗑
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show | At the temporo-parietal junction
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show | Midbrain
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When is treatment for carotid stenosis considered? | show 🗑
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show | At the Foramen of Monro (a 'channel' that lies between the lateral ventricles and the third ventricle)
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show | Disorder in which protein deposits in brain damage vessels, causing micro hemorrhages--and important risk factor for ICH!!
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show | Statins
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show | NECT (Non-contrast CT)
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show | Before: NPO 4-6hrs, PT/INR, allergies to shellfish/iodine, consent
After: Bedrest 6hrs, HOB only to 30 degrees, assess for bleeding/circulation, avoid flexing & hyper flexing affected extremity for 12-24hrs, liberal fluid intake
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show | Cerebral Angiography
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show | More sensitive than NECT for ischemic strokes
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What is digital subtraction angiography (DSA) used for? Particularly, what is it "best" at detecting? | show 🗑
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What is TCD used for? | show 🗑
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show | biopsy
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What would be the characteristics of CSF after an LP that would indicate SAH? | show 🗑
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show | PFO (patent foramen ovale)
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What is the target SpO2 in stroke patients? | show 🗑
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What is desired EMS arrival time to possible stroke patient? | show 🗑
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What are the three structures of the brain stem (in order)? | show 🗑
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What are the structures of the basal ganglia? | show 🗑
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What are the structures of the diencephalon? | show 🗑
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What are the structures of the limbic system? | show 🗑
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Are strokes more prevalent in men or women? | show 🗑
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Does family history of stroke affect one's risk? | show 🗑
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What is the #1 modifiable risk factor for preventing both ischemic and hemorrhagic stroke? | show 🗑
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show | Doubles risk
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Having D.M increases stroke risk by how much? | show 🗑
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show | Less than 7
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show | 4-5x times risk; strokes usually larger
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What are ICH risk factors? | show 🗑
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show | Yes, but very weak, in comparison to ischemic
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show | Smoking (#1), ETOH, HTN, family history, sex (women, men only after 50 more prevalent), race (blacks)
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Approximately how many neurons are lost every minute in large strokes? | show 🗑
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What is the most important 'patient history' information for EMC crews to attain from a suspected stroke patient? | show 🗑
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What is the goal time for stroke patient to see MD? | show 🗑
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What is the goal time for stroke patient to see stroke team? | show 🗑
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show | 25min
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show | 45min
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What is the goal time for patient to get TpA? | show 🗑
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What will appear white (hyperdense) in a CT scan? | show 🗑
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What will appear dark gray (hypodense) in CT scan? | show 🗑
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What will appear black in CT scan? | show 🗑
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show | Approximately 6-8hrs
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show | CT scan
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show | Immediately
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show | 24-72hrs
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show | Admit through discharge
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What is one of the drawbacks of the NIH? | show 🗑
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If a patient has a NIH score of 14 or more, where can you anticipate he or she will be discharged to? | show 🗑
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If a patient has a NIH of 6-13, where can you anticipate he or she will be discharged to? | show 🗑
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show | Home
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show | 25%
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show | It is of DEBATE, yet current consensus is a GOAL of 140-180mg/dL
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What is the ideal blood glucose for an ICH stroke patient? | show 🗑
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What is the ideal blood glucose for a SAH stroke patient? | show 🗑
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What is one of the leading causes of epilepsy in the older population? | show 🗑
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show | ONLY for SAH and for a short term (3-7days)
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show | temporal lobe or cerebral cortex
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show | 25%
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show | 50% in ICU and stroke unit, and up to 11% in post-acute rehab
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What is the rate of urinary incontinence in stoke patients? | show 🗑
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When can heparin safely be started as DVT prophylaxis of ICH and SAH patient? | show 🗑
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show | Controversial, currently no 'ideal'
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When can warfarin be safely restarted in a stroke patient? | show 🗑
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What are the major functions of the parietal lobe? | show 🗑
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What are the major functions of the occipital lobe? | show 🗑
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What are the major functions of the temporal lobe? | show 🗑
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Strokes in what area can leave deficits on both 'sides' of the body? | show 🗑
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What are the major signs/symptoms of a lateral medulla (medullary) stroke? | show 🗑
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What are the major signs/symptoms of a medial medulla (medullary) stroke? | show 🗑
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What are the major signs/symptoms of a cerebellar stroke? | show 🗑
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show | Hemiparesis, cerebellar symptoms; Lacunar syndromes --> pure motor hemiparesis, transient dizziness, diplopia, nystagmus, dysarthria, dysphagia, ataxic hemiparesis
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show | Behavior/emotions, contains motor cortex in posterior aspect; Broca's area (expressive aphasia)
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What are major signs/symptoms of midbrain strokes? | show 🗑
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What is the only FDA approved Rx for acute stroke? | show 🗑
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show | 0.9mg/kg to a max dose of 90mg
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At what rate is tPA administered? | show 🗑
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show | Stop TPA, notify MD, anticipate STAT CT--there are no standardized measures to treat patient if they have indeed bled post TPA--cryoprecipitate and/or platelets can be considered
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What are the major S/S of a medial thalamic stroke? | show 🗑
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What can carotid bruit indicate? | show 🗑
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show | Osler nodes and Janeway lesions are nodes/ulcerations on hands and feet (osler nodes are painful) that indicate INFECTIVE ENDOCARDITIS--a big risk factor for stroke
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show | STEROIDS mainline, can consider immunosuppressants
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What is normal CPP (Cerebral Perfusion Pressure)? | show 🗑
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What is the treatment for cocaine induced hypertension? | show 🗑
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show | On the affected side
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show | 5-15mmHg (greater than 20 is considered 'increased')
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show | MANNITOL to reduce cerebral edema (can also consider hypertonic saline, ventricular drains, decompresive surgery, mild hypocarbbia [hyperventilation to reduce CO2, which vasodilates])
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show | 30-35mmHg
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show | NO, not recommended
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show | 5-7 days, which is the same as the life of platelets themselves (therefore, considered irreversible)
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show | 5-7 days, which is the same as the life of platelets themselves (therefore, considered irreversible)
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Are Brilanta and Effient ideal for secondary stroke prevention? | show 🗑
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What is the half-life of Warfarin? What is the onset? | show 🗑
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Are novel anticoagulants (Pradaxa, Eliquids, Xarelto) indicated for A-FIB CAUSED by a HEART VALVE ISSUE? | show 🗑
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Orolingual angiodema is a potential side effect of what drug? | show 🗑
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What should BP be BEFORE starting tPA? What about DURING & AFTER tPA? | show 🗑
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How often should vitals be checked during tPA infusion? | show 🗑
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How long does TPA remain in body? | show 🗑
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show | -Over 80yrs old
-Pt. on anticoagulant therapy (regardless of INR)
-NIH greater than 25
-Patients with history of stroke AND diabetes
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show | #1 BASAL GANGLIA, #2 is thalamus
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A stroke in what area can cause ipsilateral 'drunk-like' motor dysfunction? | show 🗑
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show | Locked-in syndrome
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show | Atrial fibrillation
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What is the 'threshold' GCS score that would indicate a need for intubation? | show 🗑
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show | Only treat if higher than 220/120; after 24hr period, we can begin to decrease BP by 10-15%
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show | Re-establish blood flow and save the penumbra
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When and for how long should nimodopine be started on a SAH patient? | show 🗑
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show | 60mg q4h for 21 days (may do 30mg q2h if patient becomes hypotensive)
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show | DECREASES INCIDENCE/prevents vasospasm, DOES NOT TREAT IT
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show | Lets us know if a stroke was cardioembolic (from heart) or thrombotic (from cranial arteries)
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show | MRI/MRA with gradient echo
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When should LP be considered for SAH diagnosis? | show 🗑
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show | Retraining the 'good' arm of the patient to "force them" to use the affected (weaker) side.
ONLY USE WITH ARMS--IF USED IN LOWER EXT, CAN CAUSE FALLS!
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show | Tolerate 3hrs of therapy 5 days a week, need two or more disciplines (OT/ST/PT), be medically stable
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When is the peak incidence of vasospasm after SAH? | show 🗑
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show | A chronic, vaso-occlusive disease that leads to narrowing and eventual occlusion of the internal carotids and branching vessels. It is very prominent in YOUNG ASIAN WOMEN.
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How is Moyamoya disease treated? | show 🗑
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show | CVT is a rare type of stroke in which a clot forms in the dural sinuses or the cerebral veins.
It is treated with acute anticoagulation, start with hep. drip, then oral for a few months; closely monitored
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What is the standard treatment for arterial dissections? | show 🗑
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What is the standard treatment for AVM's? | show 🗑
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How many stroke core measures are there? | show 🗑
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show | lack of CSF absorption
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What causes obstructive (non-communicating) hydrocephalus? | show 🗑
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What is the penumbra? | show 🗑
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show | NECROTIC pathway (cells die due to lack of O2 and sugar) and APOPTOTIC pathway (cells die due to 'programmed' death since the one's around them are dying)
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show | Release of thrombin at site, vasogenic edema, blood-brain barrier disruption, inflammatory response
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show | Saccular (also known as berry aneurysms) [which are the most common], and fusiform
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show | Transient blindness in one eye; common with internal carotid (ICA) strokes [because the ophthalmic artery branches from the ICA]
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What is Marcus Gunn pupil and what can cause it? | show 🗑
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What are watershed strokes? What generally causes them? | show 🗑
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show | Defined as ipsilateral cerebral blood flow above brain tissue needs; can occur after revascularization (carotid stent or endarterectomy, TPA)
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What are s/s of reperfusion syndrome? | show 🗑
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What is the treatment for reperfusion syndrome? | show 🗑
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show | aSAH
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show | INR 1.7 or less (PT of 15 or less)
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Angioedema is a common side effect of what medication? | show 🗑
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What is the treatment of choice for patients with SYMPTOMATIC carotid stenosis and greater than 70% occlusion? | show 🗑
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In patients with a patent foramen ovale (PFO), what is the ideal treatment? | show 🗑
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show | Exercise and ROM stretching
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show | Teaching a patient to be self-sufficient, decrease dependence on others, and achieve the highest functional level realistically possible
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What is a common side effect of Coumadin (aside from bleeding)? | show 🗑
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