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CP Bio Genetics

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Question
Answer
what does homozygous mean?   two of the same alleles  
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what does heterozygous mean?   two different alleles  
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what does homozygous dominant mean?   two dominant alleles  
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what does homozygous recessive mean?   two recessive alleles  
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what is an allele?   a version of a genetic trait  
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what is genetics?   the study of inheritance/heredity  
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who is the father of modern genetics?   Gregor Mendel  
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what is genotype?   the alleles an organism has- the "letters"  
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what is phenotype?   the expression of the organism's alleles - the "looks/traits"  
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what is a mutation?   a change in the DNA  
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are all mutations harmful?   no- some are harmful, some are beneficial and some don't cause any noticeable changes.  
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what is another word for regular chromosomes?   autosomes  
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what is another phrase for the X and Y chromosome?   sex chromosomes  
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how many alleles typically control a trait?   two  
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how many alleles control blood type?   three  
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when a trait is controlled by more than 2 alleles it is an example of _____ inheritance.   multiple alleles  
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what do you call a diagram of several generations of family members that shows the occurrence of certain genetic characteristics?   pedigree  
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what do you call a diagram that shows the genotypic and phenotypic outcome of crosses between two organisms?   punnet square  
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why do sex-linked diseases show up in males more than females?   females can be a carrier (and not have the disease) but since males only have on X chromosome they cannot be a carrier. They either have the sex-linked disease or they dont  
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what gender is XX   female  
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what gender is XY   male  
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who determines the sex of the child?   dad - he is the only one that can pass down a "y" chromosome  
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in a testcross the unknown genotype is crossed with...   a homozygous recessive individual.  
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why are testcrosses done?   to determine an unknown dominant genotype  
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what is a dihybrid punnett square?   one that shows two traits being tracked  
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what is a monohybrid punnett square?   one that shows one trait being tracked  
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complete dominance   when heterozygoous and homozygous dominant individuals have the same phenotype  
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incomplete dominance   when an individual displays a trait that is intermediate (blended) between the two parents  
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codominant   when both alleles for a trait are expressed in a heterozygous individual.  
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law of segregation   when the two alleles for the same trait separate when egg/sperm are formed  
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law of independent assortment   the alleles of different genes separate independently of one another during the formation of egg/sperm  
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germ cell or gamete   egg or sperm  
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sex-linked trait   a trait on a sex chromosome  
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linked gene   genes that are inherited together (are very close together on a chromosome)  
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give an example of linked genes in humans   red hair and freckles  
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chromosome map   a map of genes on a chromosome.  
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if genes are only a few map units apart then they are probably...   linked genes  
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germ-cell mutation   mutations that do not affect the person but occur in their sex cells so they can be passed down to that person's offspring  
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somatic-cell mutation   mutations that affect the person but are not passed down to that person's offspring  
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give an example of a somatic-cell mutation   some types of skin cancer (you can get from overexposure to the sun)  
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deletion mutation   loss of a piece of a chromosome  
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inversion mutation   when a chromosome segment breaks off, flips around, and reattaches  
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translocation mutation   when pieces of NON-homologous chromosomes break off and reattach to each other  
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nondisjunction   when a chromosome fails to separate correctly and one gamete receives an extra copy of a chromosome while the other receives no copy.  
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which type of mutation causes down syndrome?   nondisjunction at the 21st chromosome  
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point mutation   a change at one single gene  
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frameshift mutation   a deletion that causes the entire reading frame a gene to shift and no longer "make sense"  
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what type of mutation is a "substitution"   point mutation  
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what type of mutation is a "insertion"   frameshift mutation  
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pedigree   family tree that can show genetic traits  
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polygenic   traits influenced by several genes  
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give examples of polygenic traits   eye color, hair color, intelligence, height, skin color...  
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what do you call the field of study that looks "above the genome" to see how the environment changes an organism's DNA?   epigenetics  
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sex-influenced trait   a trait that is influenced by a gender's hormones  
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give an example of a sex-influenced trait   "pattern baldness" is more prevalent in men because they have more testosterone. the testosterone interacts with the gene to produce baldness.  
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what are two ways genetic counselors can test a pregnant woman for genetic conditions?   amniocentesis and chorionic villus sampling  
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what molecule can turn off and on genes?   methyl groups  
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when are some critical times during a person's life that their epigenome might change?   puberty and pregancy  
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what are some factors that can cause changes in the epigenome?   stress, diet, exercise, chemicals in the environment.  
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are changes in the epigenome reversible?   yes  
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how does a mother rat grooming/licking her pups affect the pup's epigenome?   more grooming turns on a gene that is beneficial to mice health.  
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