Pharm (Test 3)
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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| Propofol induces a state of general anesthesia by what action? | activation of GABA to induce the opening of Cl- channels
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| What makes propofol an ideal drug for the outpatient setting? | rapid metabolic clearance, short 1/2 life, antiemetic effects
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| Which of the following is a factor that exacerbates Propofol induced hypotension? | speed of injection
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| Which of these patient types is more prone to have a significant drop in CO w/ propofol? | 60 y/o w/ a history of impaired ventricular function
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| What makes propofol a great choice for use w/ LMA? | upper airway reflexes are depressed better than barbiturates
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| What of the following is not a contraindication for propofol administration? | chronic history of asthma
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| Clonus, spontaneous movement, and twitching after receiving propofol indicates? | excitatory phenomenon
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| Which of the following is true regarding propofol administration? | admin. should be complete w/in 6hrs, composition supports bacterial growth, should be used w/in 6hrs even if containing preservatives
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| What is the appropriate dose of propofol for induction of a healthy adult? | 2-2.5mg/kg
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| What's the propofol infusion dose for moderate sedation for a healthy pt? | 50mcg/kg/min
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| Ketamine is classified as... | dissociative IV anesthetic
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| Which is true of ketamine's binding action? | binds non-competitively to NMBA receptors
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| Should be administered prior to ketamine to avoid negative hallucinogenic effects? | benzos
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| Why would a prudent CRNA administer glycopyrrolate prior to giving a pt ketamine? | antisialogogue effect
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| Selection of ketamine for induction for an "acute abdomen" would be appropriate d/t? | it would maintain CO and BP
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| NSAIDS are contraindicated in which pt? | aspirin allergy, nasal polyps, asthma, and renal failure
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| What is the MOA for NSAIDS? | inhibits cyclooxygenase and prostaglandinsynthesis pathways
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| Slight BP elevation may be seen w/ NSAID administration d/t? | inhibition of prostaglandins
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