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Definitions

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Term
Definition
Anaphylaxis   Hypersensitivity reaction involving IgE antibodies, mast cells, basophils  
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Mast cells   Cell type found throughout body contains histamine & other substances that stimulate vasodilation  
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Basophils   Granulocyte/ Leukocyte Takes up basicdye Not phagocytic Receptor for IgE IC region  
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Degranulation   Release of contents of secretory granules from mast cells or basophils during anaphylaxsis.  
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Histamine   Subtance released by tissue cells that causes vasodilation. Capillary permeability, and smooth muscle contraction  
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Systemic Anaphylaxis   Hypersensitivity reaction causing vasodilation & resulting in shock/anaphylactic shock  
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Desensitization   Prevention of allergic-inflammatory responses  
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MHC   Major Histocompatibiltiy Complex- Genes that code for histocompatibility antigens aka HLA  
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HLA   Human leukocyte Antigen Complex, Human cell surface antigens  
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Privileged site   Area of body or tissue that doesn't illicit an immune response  
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Stem cells   Undifferentiated cell that gives rise to a variety of specialized cells  
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Autograft   Tissue graft from one's self (self)  
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Isograft   Tissue graft from a genetically identical source (Twin)  
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Allograft   Tissue graft NOT from genetically identical donor (Not twin or self)  
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Xenotransplant   Ation product- Tissue graft from another species/ xeongraft  
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Immune surveillance   Body's immune response to cancer  
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Spectrum of activity   Range of distinctly different types of microorgansims affected by an antimicrobial drug  
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Broad-spectrum antibiotic   Effective against a wide range of both gram- & gram+ bacteria  
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Superinfection   Growth of a pathogen that has developed resistance to an anti-microbial drug being used; growing of opportunistic pathogen  
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Bactericidal   Kill microbes directly- Bactericide Antimicrobial drugs  
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Bacteriostatic   Prevents microbes from growing (bacteriostasis)  
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Synergism   Principle where the effectiveness of 2 drugs used simultaneously is greater that that of either of either drug used alone  
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Antagonism   Two drugs are less effective than either alone. Competition among microbes  
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Extremophile   Microbe organism that lives in environment extremes of temp, acidity, alkalinity, salinity or pressure  
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Symbiosis   Living together of two different organisms or populations  
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Bioremediation   Use of microbes to remove an environmental pollutant  
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Coliforms   Aerobic or Faculatively anaerobic Gram- Non-endospohore forming Rod Shaped bacteria  
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