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Exam 5
Definitions
| Term | Definition |
|---|---|
| Anaphylaxis | Hypersensitivity reaction involving IgE antibodies, mast cells, basophils |
| Mast cells | Cell type found throughout body contains histamine & other substances that stimulate vasodilation |
| Basophils | Granulocyte/ Leukocyte Takes up basicdye Not phagocytic Receptor for IgE IC region |
| Degranulation | Release of contents of secretory granules from mast cells or basophils during anaphylaxsis. |
| Histamine | Subtance released by tissue cells that causes vasodilation. Capillary permeability, and smooth muscle contraction |
| Systemic Anaphylaxis | Hypersensitivity reaction causing vasodilation & resulting in shock/anaphylactic shock |
| Desensitization | Prevention of allergic-inflammatory responses |
| MHC | Major Histocompatibiltiy Complex- Genes that code for histocompatibility antigens aka HLA |
| HLA | Human leukocyte Antigen Complex, Human cell surface antigens |
| Privileged site | Area of body or tissue that doesn't illicit an immune response |
| Stem cells | Undifferentiated cell that gives rise to a variety of specialized cells |
| Autograft | Tissue graft from one's self (self) |
| Isograft | Tissue graft from a genetically identical source (Twin) |
| Allograft | Tissue graft NOT from genetically identical donor (Not twin or self) |
| Xenotransplant | Ation product- Tissue graft from another species/ xeongraft |
| Immune surveillance | Body's immune response to cancer |
| Spectrum of activity | Range of distinctly different types of microorgansims affected by an antimicrobial drug |
| Broad-spectrum antibiotic | Effective against a wide range of both gram- & gram+ bacteria |
| Superinfection | Growth of a pathogen that has developed resistance to an anti-microbial drug being used; growing of opportunistic pathogen |
| Bactericidal | Kill microbes directly- Bactericide Antimicrobial drugs |
| Bacteriostatic | Prevents microbes from growing (bacteriostasis) |
| Synergism | Principle where the effectiveness of 2 drugs used simultaneously is greater that that of either of either drug used alone |
| Antagonism | Two drugs are less effective than either alone. Competition among microbes |
| Extremophile | Microbe organism that lives in environment extremes of temp, acidity, alkalinity, salinity or pressure |
| Symbiosis | Living together of two different organisms or populations |
| Bioremediation | Use of microbes to remove an environmental pollutant |
| Coliforms | Aerobic or Faculatively anaerobic Gram- Non-endospohore forming Rod Shaped bacteria |