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Pathology Q3

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Term
Definition
hyperemia   a condition which refers to excess blood in a body part  
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active hyperemia   excess blood in a body part which was actively, or purposely, taken there by the arterial system in the body  
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active physiological hyperemia   if the active hyperemia results from a normal, everyday, healthy bodily function  
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active pathological hyperemia   if the active hyperemia is a result of some disease process  
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passive hyperemia   occurs when venous drainage from an area is decreased *always pathological *localized or generalized  
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localized passive hyperemia   occurs due to formation of a blood clot in a vein, thickening of vessel walls, and/or pressure from an outside lesion  
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generalized passive hyperemia   normally a result of a heart disorder which affects the efficiency of the heart's pumping action  
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hypostatic congestion   blood settling to the dependent parts of the body when gravity overcomes the normal flow of blood through the circulatory system *caused by reduced pressure from the heart  
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cyanosis   bluish discoloration of tissues due to lack of oxygen  
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thrombosis   the formation of a solid mass, or blood clot, within the heart or vessels of the body *abnormal  
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thrombus   solid mass, or blood clot, that forms within the heart or blood vessels; stays where it forms  
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embolism   the condition of an object having floated through the bloodstream and causing an obstruction of a vessel  
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embolus   a fragment of a blood clot; moves through vessels  
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causes of thrombosis   injury to the lining of the heart or vessels diseases of the blood itself slowing of the blood flow  
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causes of embolism   when a thrombus or piece of thrombus breaks loose and lodges elsewhere in the body clumps of bacteria, parasites, or tumor cells fat globules foreign particles air or gas bubbles  
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ischemia   decreased blood flow to a body part; causes lack of oxygen delivery to the affected part  
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causes of ischemia   thrombus atherosclerosis pressure from a growing tumor  
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infarction   an area of tissue which was deprived of it blood supply dies as a result of ischemia  
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ischemic necrosis   infarction  
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infarct   area of dead tissue caused by ischemia  
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dry gangrene   ischemic necrosis  
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moist/true necrosis   necrotic tissue which has been invaded by bacteria; often associated with disturbances to the venous return of blood from an area  
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causes of moist/true necrosis   crushing injuries of the toes & feet freezing of the tissues which occurs during frostbite diabetes mellitus  
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hemorrhage   the escape of blood form the vascular system  
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main reason for hemorrhage   a break in the walls of a vessel  
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petechiae   pin-point hemorrhages  
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ecchymosis   larger irregular patches of hemorrhage in the tissue (bruises); localized to area of trauma & circumscribed  
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purpura   widespread areas of hemorrhage into the skin or mucous membranes; not localized nor circumscribed  
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hematoma   tumor-like swelling filled with blood; ex: blood blister  
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melena   very dark, tarry feces or vomitus  
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hemothorax   bleeding into the pleural cavity  
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hemapericardium   bleeding into the pericardial cavity  
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hemoperitoneum   bleeding into the peritoneal cavity  
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hemoptysis   blood in the sputum (or from the lungs)  
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hematemesis   blood in the vomit (or from the stomach)  
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epistaxis   bleeding from the nose  
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coagulation   the process of blood changing from a liquid, free-flowing form, into a semisolid state  
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circulatory shock   the condition which results from a serious reduction of blood flow in the body, resulting in reduced oxygen supply to the tissues  
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characteristics of circulatory shock   - state of collapse - depressed vital signs - weak, rapid pulse - low blood pressure - shallow breathing - cold & clammy skin, especially in the extremities  
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syncope   fainting; caused by temporary decrease of blood flow to the brain  
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edema   an excess accumulation of fluid in the tissues of the body; extravascular  
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pitting edema   tissues become so waterlogged that they take on a doughy consistency and retain the impression of a fingerprint when pressed upon  
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main causes of edema   - heart failure - venous or lymphatic obstruction - increased capillary permeability, such as that which occurs during inflammation - decreased osmotic pressure of plasma proteins  
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anasarca   generalized or widespread edema  
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exudate   edema which collects around an inflammation site  
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hydrothorax   edema of the pleural cavity  
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hydopericardium   edema of the pericardial caivty  
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ascites   edema of the peritoneal cavity  
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dehydration   decrease in total body fluids; a.k.a. dessication  
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causes of dehydration   - high body temperature during febrile diseases - high environmental temperatures, which also cause excessive sweating - gastrointestinal diseases which result in excessive vomiting or diarrhea - glandular diseases  
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plasma   the liquid portion of blood, which consists of approximately 90% water, fibrin, salts & proteins  
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thrombocytes   platelets/clotting cells  
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erythrocytes   red blood cells  
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erythrocytes   carry oxygen to the tissues of the body & remove carbon dioxide; most numerous of the blood cells  
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leukocytes   white blood cells  
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leukocytes   important in the body's defense mechanisms, such as phagocytosis & antibody formation  
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types of leukocytes   1. neutrophils 2. eosinophils 3. basophils 4. lymphocytes 5. monocytes  
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platelets/thrombocytes   involved in the process of clot formation  
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anemia   a decrease in the number of red blood cells and/or hemoglobin  
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symptoms of anemia   weakness, fatigue, shortness of breath upon exertion, lightheadedness  
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primary anemia   decreased production of red blood cells  
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secondary anemia   increased loss or destruction of red blood cells  
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pernicious anemia   deficiency disease that results from a lack of vitamin B12 being absorbed from the digestive tract, which is important in the normal development of blood cells, including red blood cells (a primary anemia)  
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symptoms of pernicious of anemia   smooth, red, painful tongue & damage to the nervous system  
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aplastic anemia   virtual stoppage of blood cell production in the bone marrow; most serious type of anemia; idiopathic (a primary anemia)  
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sickle-cell anemia   genetic defect in the manufacture of hemoglobin that results in abnormal crescent-shaped red blood cells (hemolytic/secondary anemia)  
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erythroblastosis fetalis   problem of blood incompatibility between a mother and her unborn fetus; mother who is Rh- carries a child who is Rh+ (hemolytic/secondary anemia)  
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leukocytosis   an increase in the number of circulation white blood cells, and is an important defense mechanism of the body when it occurs in a temporary, or transient fashion (iron deficiency anemia)  
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leukemia   a malignancy of the hemopoietic tissues of the body, and is sometimes referred to as "cancer of the blood"  
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leukopenia   decrease in white blood cells  
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polycythemia   increase in the number of blood cells in the body  
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erythrocytosis   increase in red blood cells  
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hemophilia   hereditary bleeding disorder, characterized by a greatly prolonged clotting time for blood; sex-linked inherited disorder; affect males, transmitted by females  
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thrombocytopenia   decreased number of platelets or thrombocytes in the blood  
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purpura (thrombocytopenic purpura)   widespread, spontaneous hemorrhages into the skin and mucous membranes  
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ecchymosis   bruise-like patches of hemorrhage under the skin  
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petechiae   small, red spots of hemorrhage, often described as "pinpoint" hemorrhages  
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