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Veterinary Cardiovascular

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Question
Answer
Positive inotropic general   Increase cardiac output by increasing the strength of contractions, increase contractility  
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digoxin   elixer has higher bioavailability, +ionotrope, not commonly used anymore, SE: GI upset, arrythmias (esp, if already hypokalemic)  
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Epinephrine   + ionotrope, used in emergency, sympathiomimetic, used in CPR, IV ONLY  
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Dopamine   +ionotrope, CPR, IV ONLY  
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Dobutamine   +ionotrope, sympathiomimetic, use in CPR, IV ONLY  
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Pimobendan   Vetmedin, +ionotrope, vasodilator  
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Quinidine   Antiarrythmic, used in atrial fibrillation/VPC SE: GI upset, weakness, hypotension, horses (urticaria)  
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Procainamide   Antiarrythmic, atrial fibrillation/VPC's SE: GI upset, weakness, hypotension  
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Lidocaine   Antiarrythmic, 1st pass, no EPI (use neat!!), VPC's, cats are sensitive to lidocaine, SE: drowsy, seizures, ataxia, tremors, GI upset  
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Tocainide   Antiarrythmic, same as lidocaine  
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Propranolol   Antiarrythmic, beta blocker, treats atrial and ventricular tachyarrthymia and decreased blood pressure, SE: depression, hypotension, bronchoconstriction  
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Verapamil/Diltiazem   Antiarrythmic, negative chronotrope to treat atria tacyarrhythmias, SE: bradycardia, hypotension, depression, pulmonary edema, constipation  
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Atropine   Antiarrythmic, positive chronotrope, blocks parasympathetic system, regulates HR, speeds HR up  
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Hydralazine   Arteriolar dilator SE: increased HR, hypotension, Na/H2O retention if not given concurrently with a diuretic, GI upset  
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Nitroglycerin   Venodilator, Topical ointment, SE: rash at site, hypotension, headaches in people (animals?), wear gloves when using, rub it in in ear/groin/axilla, rotate sites to decrease the possibilities of a rash  
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Captropril   ACE inhibitor  
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ACE inhibitors in General   Cause both vasodilation and decreased Na and H2O retention, SE: hypotension, hyperkalemia (careful with K sparing diuretics), excretion: captopril and enalapril 95% by kidneys, benazepril 50:50 liver:kidney, decrease pre and after load  
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Enalapril   Enacard  
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Benazepril   Fortekor  
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Cardiovascular drugs in general   Low TI, liver and kidney function required, many drug interactions, SE commonly due to toxicity  
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