Pharm (Test 2)
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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| Which opioid isn't taken up by the lungs in first pass? | morphine
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| Which opioid causes an increase in HR? | meperidine
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| Which opioid can be used to treat post-op shivering? | meperidine
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| What is the most potent opioid currently available? | sufentanil
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| Which opioid is the best drug of choice for a single, brief stimulus? | alfentanil
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| Which opioids are the best drugs of choice of a retrobulbar block? | alfentanil and remifentanil
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| Which opioid can be given during liver transplant during phase when pt has no liver? | remifentanil
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| Which opioid's context sensitive half-time is independent of length of infusion? | remifentanil
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| Which opioid has a rapid equilibration that allows for titration almost like a vaporizer? | remifentanil
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| Which opioid of the fentanyl class has the smallest volume of distribution? | remifentanil
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| Which opioid was discovered during search for synthetic atropine? | meperidine
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| Which opioid is a naturally occurring derivative from the poppy plant? | morphine
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| Which 2 opioids cause histamine displacement? | morphine and meperidine
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| Which opioid can cause an inc. in ICP, even w/ unchanged PaCO2? | fentanyl
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| Which opioid can cause myoclonus? | fentanyl
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| A dose of 30mcg/kg of which opioid can cause a change in SSEP? | fentanyl
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| Which opioid has a greater analgesic potency in women than men? | morphine
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| 80% of this opioid leaves the plasma in <5 min. | fentanyl
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| Pre-induction dose of this opioid may cause apnea w/o loss of consciousness. | sufentanil
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| Only <0.1% of the administered dose of this opioid enters the CNS at peak plasma cntn. | morphine
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| Doses of >2mg/kg of this opioid can cause myocardial drpression. | meperidine
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| Which opioid sensitizes the labyrinth apparatus, resulting in dizziness and PONV? | meperidine
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| Which opioid is a poor cough suppressant? | meperidine
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| Which opioid has better oral absorption than morphine? | meperidine
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| Which opioid, when given with MAOI's, may cause serotonin syndrome? | meperidine
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| Which opioid was designed for anesthesia? | fentanyl
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| Which opioid is highly linked to renarcotization? | fentanyl
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| Which opioid has prolonged duration in pts undergoing abdominal aortic surgery involving infrarenal aortic cross-clamping? | fentanyl
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| Which opioid can cause reflex coughing? | fentanyl
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| Which opioid requires d/c'ing the infusion 30-45 min prior to emergence? | sufentanil
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| 30mcg/kg of this opioid provides maximal blunting for laryngoscopy. | alfentanil
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| Which opioid produces more euphoria than fentanyl? | alfentanil
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| 96% of this opioid is cleared w/in 60 min of administration. | alfentanil
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| Which opioid requires d/c'ing the infustion 15-25 min prior to emergence? | alfentanil
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| 15mcg/kg of this opioid blunts SBP and HR response to laryngoscopy. | alfentanil
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| 30mcg/kg of this opioid blunt catecholamine response to laryngoscopy. | alfentanil
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| Which opioid has a lower incidence of PONV than the other fentanyl class opioids? | alfentanil
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| 99.8% of this opioid is eliminated during distribution. | remifentanil
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| Which opioid has a context-sensitive half time of 4 min? | remifentanil
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| Which opioid produces a 30% dec. in SBP 2 min after administration? | remifentanil
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| Which drug is the drug of choice for pts having a craniotomy or carotid endarterectomy? | remifentanil
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| Which opioid has less euphoria than the other opioids? | hydromorphone
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| Which opioid is commonly used in terminally ill pts? | hydromorphone
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| Only 10% of this opioid is in ionized form at physiologic pH. | alfentanil
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| Is it difficult to diagnose an overdose of this opioid b/c the BP at the minimum effective dose and the BP at 5X that dose are the same. | sufentanil
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| Which opioid has 60% uptake by the lungs during first-pass? | sufentanil
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| 5-8mcg/kg of this opioid dependably blunts the sympathetic response of laryngoscopy. | fentanyl
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| Metabolism of this opioid has great patient variability d/t P-450 and CYP3A enzyme variability. | alfentanil
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| Hypothermia slows clearance of this opioid by 20%. | remifentanil
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| Which opioid is ideal for quick neuro assessments post-op for craniotomy and carotid endarterectomy procedures? | remifentanil
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| Which 2 opioids cause direct relaxation of aortic smooth muscle? | sufentanil and alfentanil
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| Which 2 opioids have cardiac protective effect to reduce the size of an MI when administered prior to occlusion of coronary artery? | morphine and remifentanil
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| Which 2 opioids should be avoided in pts with renal dysfunction? | morphine and meperidine (d/t active metabolites)
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| What are 2 different treatments for post-op shivering? | Demerol and stadol
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| What are 2 ways to treat neuraxial opioid-induced pruritis? | nubain and narcan
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