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Pathology Terminolog

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Term
Definition
Pathology   Study of Disease & Disease Process  
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Myriad Nox ious Agents   Causes disease  
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Disease is caused by   Damage to Cellular and Tissue injury the membrane or Enzymes  
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Damage to the Membrane or enzymes create   Lesions  
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Cells need   Nutrients Oxygen Protection from toxins  
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Clinical pathology   Damaged cells release certain products that can be seen in lab tests  
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Somatic Death   Disappearance of Life from individual  
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Necrosis   Local Death of Tissue in LIVING ANIMAL  
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Anoxia   lack of Oxygen  
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Post Mortem Changes-Def   Changes that occur after death  
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4 PM changes   1) Cooling 2) Rigor Mortis 3) Blood changes 4) PM Degeneration  
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1) Cooling   Rate of cooling of the body -Initial -Insulation -Environment  
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2) Rigor Mortis   Stiffening of muscles 1-9 HOURS after death -Contraction of Muscle fibers due to energy supply decrease  
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3) Blood Changes   a) Pool due to gravity b) Clot  
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4) PM Degeneration   Decay of body an organs involved in two ways a) Autolysis b) Putrefaction  
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a) Autolysis   Breakdown of Cells and tissue cause by ENZYMES from BODY  
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b) Putrefaction   Break down of Cells and tissue cause by BACTERIA from ENVIRONM. or BODY (microorganisms)  
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Hypoxia   Lack of Oxygen  
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Cellular Degeneration   -Memb. Sodium-Potassium Pump dysfunction Changes intracellular and extracellular functions  
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Systemic   Effecting BODY as a WHOLE  
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Local   Specific to Area that is Effected  
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Li-que-faction   FLUID & SMALL Mol. CATABOLYSE + Removed through BLOOD STREAM & LYMPHATIC sys.  
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Sup-pur-ation   Liquefaction with PUS Formation  
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Py-o-genic Bacteria   PUS forming  
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Pus/Purlent EXUDATE   Semi-Liquid Necrotic  
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Lytic Enzymes   -Secreted by BACTERIA, DEAD TISS. CELLS & Dying NEUTRAPHILS  
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Sequ-est-ration   ENCAPSULATION without Liquefaction  
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D -esquamation + Sloughing (2 ways)   DEAD cells loosing their ATTACHMENT into space or lumen 1) Erosion 2) Ulceration  
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Erosion   Only SUPERFICIAL Epithelium  
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Ulceration   FULL thickening of Epithelium LOST -To BASMENT Memb.  
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Organisation   NECROTIC Tiss. processed with the presence of -Leukocytes =Engulf NECROTIC mat. -Capillaries -Fibroblasts=Lays down CONNECTIVE Tiss-FILLS GAPS =MATURATION  
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Regenration   =Only occurs in Cells that DIVIDE -Cells survive initial damage. Will MULITIPLE & REPLACE DEAD cells Don't occur in neurons and Cardiac mus.  
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Gangrene   -DIGESTION of Necrotic tiss. a) Toxaemia b) Sloughing  
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Toxaemia   -DECOMPOSITION of bodies PROTEINS and removed through BLOOD STREAM and LYMPHATICS  
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A- trophy (A-Accident )   " SHRINKED" Dec in Size e.g Disuse Atrophy -Broken Leg  
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Hypertrophy   -INC in SIZE due to inc CELL SIZE  
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Meta-plasia   "CHANGE" from 1 CELL to Another  
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Hypo-plasia Hyp o -plas i a   " INCOMPLETE" Growth Extremes: Aplasia Agensis Atresia  
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Aplasia A-p (Flip) b   "ABSENSE"  
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Agenisis g-Goal e-Embryo   "FAILURE" to develop in Embryo  
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Atresia a-Ass   "CLOSURE" or "ABSENCE" of LUMANL struct.  
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Dysplacia   "LACK" of Histological ARCHITECTURE -Jumbled distribution of tissue  
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Distribution of Circulation   inadequate CIRCULATION of BLOOD  
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Hyper-aemia   INC - blood FLOW to Area  
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Congestion   Impeded Flow "OUT"  
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hypostatic   'POOLING' of blood  
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Ischaemia   'WITHOUT' BLOOD -inadequate blood supply  
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Volvus   an OBSTRUCTION caused by TWISTING of the stomach or intestine.  
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Infarction   'LOCALISED' Area of "NECROSIS" caused by ISCHAEMIA Wedge shaped kidney  
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Anaemia   "LACK" of OXYGEN in blood  
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Acute   "QUICK" onset  
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Chronic   " LONG" onset over several days  
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Thrombus   "BLOOD CLOT" that forms in vessel during LIFE  
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Thrombosis   Formation of an "INAPPROPRIATE" Thrombus on wall of a vessel (Blood or Lymph.)  
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Vascular Stasis   "DEC" in Blood FLOW  
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Aneurysms   "DILATED" heart Chamber  
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Embo-lus   Abnormal "MASS" circulating in blood  
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Embo-lism   "ARREST" of Circulatory "MASS" in vessel  
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Throm-boem-boli   Formed from "THROMBI" -Bits of THROBUS breaking off -Travel to lungs=DEATH  
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Haemorrhage   "BLEEDING" from damaged vessels  
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Haematoma   -"LOCALISED" accum. of Blood =CLOT  
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Pete-chiae p-pin   "PIN POINT" Haemorrhage  
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Ec-chym-oses e-Educational Painting   "PAINT BRUSH" Haemorrhage  
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Bruising   -SUB Q Haemorrhage  
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Haemo-peri-cardium   Blood in Pericardium  
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Haemo-thorax   Blood in Thorax  
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Haemo-peritoneum   Blood in Abdominal cavity  
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Shock   "Failure" of Circ. Sysy. to Adequately "PERFUSE" vital Organs -vascular dilation  
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Hypo-vol-aemic Shock   DEC blood Volume  
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Vascu-lo-genic shock   INC Vascular space  
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Septic   Infected with Bacteria  
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Cardio-genic Shock   "REDUCED" cardiac Output  
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Dys-rhyth-mia   Abnormal Heart Rhythm  
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Endo-toxic Shock   Severe Vaso-dilation  
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Diuresis   -Water loss through kidneys  
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Oedema   "EXCESSIVE" Acculam. of Tiss FLUID  
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Ascites   Accum. of fluid in "PERITONEAL" cavity - causing Abdominal "SWELLING"  
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Hydrothorax   Fluid in the thorax  
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Hydropericardium   Fluid in the pericardial space  
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Anasarca   Widespread "SWELLING" of SKIN due to effusion of fluid into the extracellular space.  
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Hydrostatic Pressure (HP)   Pressure du to mol. inside the vessel  
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Osmotic Pressure   pressure needed to be applied to a pure solvent to prevent it from passing into a given solution by osmosis  
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Coloid Osmotic Pressure (COP)   Pressure due to the concn. of PROTEINS in vessel  
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Hypoalbuminaemia   DEC formation of Albumin or INC. LOSS  
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Lymphoedema   Oedema due to lymphatic syst. BREAKDOWN  
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Pulmonary Oedema   Left side of heart fails causes BACKFLOW into blood vessels  
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Cerebral Oedema   Fluid on the brain  
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Anaphylaxis   an acute allergic reaction to an antigen (e.g. a bee sting) to which the body has become hypersensitive.  
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Pleuritis   Inflammation of the pleura  
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Dermatitis   Inflammation of the skin  
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Enteritis   Inflammation of the Intestines  
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Gastritis   Inflammation of the Stomach & Intestines  
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Encephalitis   Inflammation of the brain  
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Cystitis   Inflammation of the bladder  
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Nephritis   Inflammation of the kidney  
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Osteomyelitis   Inflammation of the bone  
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Stomatitis   Inflammation of the oral cavity/mouth  
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Tonsillitis   Inflammation of the tonsils  
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Gingivitis   Inflammation of the gums  
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Causes of inflammation   Trauma Physical agents Chemical irritants Bacteria Viruses Parasites Allergic Alleries  
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