Pathology Terminolog
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Pathology | Study of Disease
&
Disease Process
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Myriad Nox ious Agents | Causes disease
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Disease is caused by | Damage to Cellular and Tissue injury
the membrane or Enzymes
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Damage to the Membrane or enzymes create | Lesions
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Cells need | Nutrients
Oxygen
Protection from toxins
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Clinical pathology | Damaged cells release certain products that can be seen in lab tests
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Somatic Death | Disappearance of Life from individual
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Necrosis | Local Death of Tissue in LIVING ANIMAL
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Anoxia | lack of Oxygen
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Post Mortem Changes-Def | Changes that occur after death
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4 PM changes | 1) Cooling
2) Rigor Mortis
3) Blood changes
4) PM Degeneration
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1) Cooling | Rate of cooling of the body
-Initial
-Insulation
-Environment
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2) Rigor Mortis | Stiffening of muscles 1-9 HOURS after death
-Contraction of Muscle fibers due to energy supply decrease
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3) Blood Changes | a) Pool due to gravity
b) Clot
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4) PM Degeneration | Decay of body an organs involved in two ways
a) Autolysis
b) Putrefaction
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a) Autolysis | Breakdown of Cells and tissue cause by ENZYMES from BODY
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b) Putrefaction | Break down of Cells and tissue cause by BACTERIA from ENVIRONM. or BODY (microorganisms)
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Hypoxia | Lack of Oxygen
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Cellular Degeneration | -Memb. Sodium-Potassium Pump dysfunction
Changes intracellular and extracellular functions
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Systemic | Effecting BODY as a WHOLE
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Local | Specific to Area that is Effected
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Li-que-faction | FLUID & SMALL Mol. CATABOLYSE + Removed through BLOOD STREAM & LYMPHATIC sys.
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Sup-pur-ation | Liquefaction with PUS Formation
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Py-o-genic Bacteria | PUS forming
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Pus/Purlent EXUDATE | Semi-Liquid Necrotic
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Lytic Enzymes | -Secreted by BACTERIA, DEAD TISS. CELLS & Dying NEUTRAPHILS
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Sequ-est-ration | ENCAPSULATION without Liquefaction
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D -esquamation + Sloughing (2 ways) | DEAD cells loosing their ATTACHMENT into space or lumen
1) Erosion
2) Ulceration
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Erosion | Only SUPERFICIAL Epithelium
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Ulceration | FULL thickening of Epithelium LOST
-To BASMENT Memb.
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Organisation | NECROTIC Tiss. processed with the presence of
-Leukocytes =Engulf NECROTIC mat.
-Capillaries
-Fibroblasts=Lays down CONNECTIVE Tiss-FILLS GAPS
=MATURATION
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Regenration | =Only occurs in Cells that DIVIDE
-Cells survive initial damage. Will MULITIPLE & REPLACE DEAD cells
Don't occur in neurons and Cardiac mus.
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Gangrene | -DIGESTION of Necrotic tiss.
a) Toxaemia
b) Sloughing
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Toxaemia | -DECOMPOSITION of bodies PROTEINS and removed through BLOOD STREAM and LYMPHATICS
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A- trophy (A-Accident ) | " SHRINKED"
Dec in Size
e.g Disuse Atrophy -Broken Leg
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Hypertrophy | -INC in SIZE due to inc CELL SIZE
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Meta-plasia | "CHANGE" from 1 CELL to Another
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Hypo-plasia Hyp o -plas i a | " INCOMPLETE" Growth
Extremes:
Aplasia
Agensis
Atresia
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Aplasia A-p (Flip) b | "ABSENSE"
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Agenisis g-Goal e-Embryo | "FAILURE" to develop in Embryo
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Atresia a-Ass | "CLOSURE" or "ABSENCE" of LUMANL struct.
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Dysplacia | "LACK" of Histological ARCHITECTURE
-Jumbled distribution of tissue
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Distribution of Circulation | inadequate CIRCULATION of BLOOD
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Hyper-aemia | INC - blood FLOW to Area
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Congestion | Impeded Flow "OUT"
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hypostatic | 'POOLING' of blood
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Ischaemia | 'WITHOUT' BLOOD
-inadequate blood supply
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Volvus | an OBSTRUCTION caused by TWISTING of the stomach or intestine.
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Infarction | 'LOCALISED' Area of "NECROSIS"
caused by ISCHAEMIA
Wedge shaped kidney
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Anaemia | "LACK" of OXYGEN in blood
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Acute | "QUICK" onset
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Chronic | " LONG" onset
over several days
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Thrombus | "BLOOD CLOT" that forms in vessel during LIFE
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Thrombosis | Formation of an "INAPPROPRIATE" Thrombus on wall of a vessel (Blood or Lymph.)
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Vascular Stasis | "DEC" in Blood FLOW
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Aneurysms | "DILATED" heart Chamber
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Embo-lus | Abnormal "MASS" circulating in blood
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Embo-lism | "ARREST" of Circulatory "MASS" in vessel
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Throm-boem-boli | Formed from "THROMBI"
-Bits of THROBUS breaking off -Travel to lungs=DEATH
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Haemorrhage | "BLEEDING" from damaged vessels
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Haematoma | -"LOCALISED" accum. of Blood =CLOT
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Pete-chiae p-pin | "PIN POINT" Haemorrhage
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Ec-chym-oses e-Educational Painting | "PAINT BRUSH" Haemorrhage
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Bruising | -SUB Q Haemorrhage
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Haemo-peri-cardium | Blood in Pericardium
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Haemo-thorax | Blood in Thorax
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Haemo-peritoneum | Blood in Abdominal cavity
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Shock | "Failure" of Circ. Sysy. to Adequately "PERFUSE" vital Organs
-vascular dilation
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Hypo-vol-aemic Shock | DEC blood Volume
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Vascu-lo-genic shock | INC Vascular space
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Septic | Infected with Bacteria
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Cardio-genic Shock | "REDUCED" cardiac Output
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Dys-rhyth-mia | Abnormal Heart Rhythm
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Endo-toxic Shock | Severe Vaso-dilation
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Diuresis | -Water loss through kidneys
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Oedema | "EXCESSIVE" Acculam. of Tiss FLUID
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Ascites | Accum. of fluid in "PERITONEAL" cavity
- causing Abdominal "SWELLING"
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Hydrothorax | Fluid in the thorax
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Hydropericardium | Fluid in the pericardial space
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Anasarca | Widespread "SWELLING" of SKIN due to effusion of fluid into the extracellular space.
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Hydrostatic Pressure (HP) | Pressure du to mol. inside the vessel
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Osmotic Pressure | pressure needed to be applied to a pure solvent to prevent it from passing into a given solution by osmosis
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Coloid Osmotic Pressure (COP) | Pressure due to the concn. of PROTEINS in vessel
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Hypoalbuminaemia | DEC formation of Albumin
or
INC. LOSS
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Lymphoedema | Oedema due to lymphatic syst. BREAKDOWN
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Pulmonary Oedema | Left side of heart fails
causes BACKFLOW into blood vessels
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Cerebral Oedema | Fluid on the brain
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Anaphylaxis | an acute allergic reaction to an antigen (e.g. a bee sting) to which the body has become hypersensitive.
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Pleuritis | Inflammation of the pleura
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Dermatitis | Inflammation of the skin
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Enteritis | Inflammation of the Intestines
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Gastritis | Inflammation of the Stomach & Intestines
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Encephalitis | Inflammation of the brain
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Cystitis | Inflammation of the bladder
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Nephritis | Inflammation of the kidney
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Osteomyelitis | Inflammation of the bone
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Stomatitis | Inflammation of the oral cavity/mouth
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Tonsillitis | Inflammation of the tonsils
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Gingivitis | Inflammation of the gums
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Causes of inflammation | Trauma
Physical agents
Chemical irritants
Bacteria
Viruses
Parasites
Allergic Alleries
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Created by:
Melissa Jones
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