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CfE Higher Vocab - Topic 7 (Sequencing), 8 (Pathway control) & 9 (Respiration)

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Term
Definition
Catabolic   A reaction which releases energy and breaks down molecules.  
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Electron transport chain   The final stage of respiration where high energy electrons and hydrogen ions are used to synthesise ATP.  
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ATP   The energy-carrying molecule used in cells because it can release energy very quickly.  
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Feedback inhibition   The first enzyme of a metabolic pathway is inhibited by the reversible binding of the final product of the pathway.  
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Fermentation   A type of respiration which takes place in the absence of oxygen.  
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Pyruvate   A molecule formed during glycolysis which, when oxygen is present, enters the matrix of the mitochondrion to start the citric acid cycle.  
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NAD   A co-enzyme which easily attaches to hydrogen ions, but releases them when they are required.  
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Anabolic   A reaction which requires energy and builds up molecules.  
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Non-competitive inhibition   A molecule binds to part of the enzyme away from the active site, and causes a change in shape of the active site of the enzyme, thereby inhibiting the binding of the appropriate substrate molecule.  
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ADP   A low energy molecule that forms ATP when a phosphate molecule is added.  
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Phosphorylation   The addition of a phosphate group.  
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ATP synthase   An enzyme which produces ATP.  
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Dehydrogenase   An enzyme which removes hydrogen ions and electrons from substrates  
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Oxaloacetate   Combines with acetyl coenzyme A to form citrate during the citric acid cycle.  
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Competitive inhibition   Occurs when an inhibitor, resembling the structure of the substrate, binds to the active site of the enzyme and blocks the binding of the substrate  
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FAD   An alternative to NAD. A co-enzyme which easily attaches to hydrogen ions, but releases them when they are required.  
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Metabolism   The chemical processes that occur within a living organism in order to maintain life.  
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Induced fit   A slight change in shape (a squeeze) of the active site of the enzyme that allows the substrate to fit perfectly  
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Citrate   Formed during the citric acid cycle when oxaloacetate combines with acetyl coenzyme.  
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Energy investment phase   The first phase of glycolysis where 2 molecules of ATP are required.  
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Glycolysis   The first stage of respiration where glucose is broken down into pyruvate.  
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Lactate   Pyruvate is converted to this molecule during fermentation/anaerobic respiration.  
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Matrix of mitrochondrion   The specific area of a mitochondrion where the citric acid cycle takes place.  
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Energy pay-off phase   The last phase of glycolysis where 4 molecules of ATP are produced.  
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Anaerobic respiration   Respiration that takes place without oxygen. Also known as fermentation.  
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