Nursing Pharmacology Antibiotic Therapy
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| Which class of ABx is Sulfamethoxazole? | Sulfonamides: Bacteriostatic
Prevent synthesis of folic acid
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| Which class of ABx is Sulfisoxazole | Sulfonamides: Bacteriostatic
Prevent synthesis of folic acid
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| What are Adverse Effects of Sulfonamides? | Hemolytic and aplastianemia, agranulocytosis, thrombocytopenia Photosensitivity, exfoliative dermatitis, SJS epidermal necrolysis
N&V, Diarrhea, pancreatitis, convulsions, cephalgia, liver and kidney problems
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| What is the prototype of the sulfonamides class? | Cotrimoxazole- Indications- UTI, Acut OM, chronic bronchitis, traveler's diarrhea
Orall route, rapid abosobtion
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| What are 4 major sub-classes of Beta Lactam Antibiotics? | Penicillins, cephalosporins, carbapenems, and monobactams
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| When was penicillin first introduced? | 1940
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| What broad spectrum antibiotic is bactericidal (inhibits cell wall synthesis) | Penicillin
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| What enzyme do some bacteria produce to become resistant to penicillins? | B-lactamase
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| Which types of bacteria is susceptible to PCN? | gram positive
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| What other sub-class of Beta Lactams is a patient also likely to be allergic to if they have an allergy to PCN? | Cephalosporins
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