Test 2 Advanced patho
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
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Shock | The physiologic state characterized by a reduction of systemic tissue perfusion resulting in decreased oxygen delivery to the cells and tissues.
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Systemic Tissue perfusion | Cardiac output and systemic vascular resistance
CO = HR x SV
Stroke volume is related to preload, myocardial contractility and after load. Affected by vessel length, blood viscosity and vessel diameter
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Cardinal Symptoms of Shock | Hypotension: absolute SBP <90 or Relative: a decrease in SBP >40
Oliguria: vol. depletion, shunting to kidney
Altered mental status: agitation, confusion, coma
Cool clammy skin: vaso constriction
Metabolic acidosis: lactate build up
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Prognosis of Shock | Depends on type and severity
Time of onset of initial treatment
Co-morbid states, development of complications
Even with treatment: septic and cardiogenic >50% mortality. Untreated: fatal
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States of Shock | Preshock
Shock
End organ dysfunction
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Preshock | Warm shock: decreased afterload (SVR)
Increased cardiac output/cardiac index
Decreased blood pressure
Sympathetic response
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Shock: cold shock | Decreased CO
Elevated SVR
Decreased perfusion
Sympathetic response
Hypothermia
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End Organ Dysfunction | Multiple organ dysfunction syndroms
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