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Test 2 Advanced patho

Shock The physiologic state characterized by a reduction of systemic tissue perfusion resulting in decreased oxygen delivery to the cells and tissues.
Systemic Tissue perfusion Cardiac output and systemic vascular resistance CO = HR x SV Stroke volume is related to preload, myocardial contractility and after load. Affected by vessel length, blood viscosity and vessel diameter
Cardinal Symptoms of Shock Hypotension: absolute SBP <90 or Relative: a decrease in SBP >40 Oliguria: vol. depletion, shunting to kidney Altered mental status: agitation, confusion, coma Cool clammy skin: vaso constriction Metabolic acidosis: lactate build up
Prognosis of Shock Depends on type and severity Time of onset of initial treatment Co-morbid states, development of complications Even with treatment: septic and cardiogenic >50% mortality. Untreated: fatal
States of Shock Preshock Shock End organ dysfunction
Preshock Warm shock: decreased afterload (SVR) Increased cardiac output/cardiac index Decreased blood pressure Sympathetic response
Shock: cold shock Decreased CO Elevated SVR Decreased perfusion Sympathetic response Hypothermia
End Organ Dysfunction Multiple organ dysfunction syndroms
Created by: pg4132