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Comprehensive Pharm 3

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Question
Answer
what are the symptoms of organophosphate poisoning   show
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show atropine + pralidoxime  
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show antagonist used to regenerate active cholinesterase  
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show increases outflow of aqueous humor  
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MOA brimonidine in tx of glaucoma   show
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MOA beta blockers in tx of glaucoma   show
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show decreas aqueous humor secretion d/t decreaed HCO3  
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show increased outflow of aqueous humor  
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show pilocarpine (direct ACh mimetic)  
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show PGF-alpha, increases outflow of aqueous humor  
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which glaucoma drugs decrease the synth of aqueous humor?   show
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show epi cholinomimetics PGF2alpa (latanoprost)  
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show muscarinic antagonist  
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show dry as a bone hot as a hare mad as a hatter red as a beet blind as a bat  
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Effects Nitrates have on: EDV BP Contractility HR Ejection time MV O2   show
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Effects B-blockers have on: EDV BP Contractility HR Ejection time MV O2   show
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effects b-blockers + nitrates have on: EDV BP Contractility HR Ejection time MV O2   show
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show block voltage dependent ca channels of cardiac and smooth muscle, reducing muscle contractility  
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In decreasing effect, which CCBs have most effect on vascular smooth muscle?   show
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show verapamil > diltiazem > nifedipine  
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show nifedipine  
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toxicity of CCBs   show
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which CCB is most similar to nitrates in effect?   show
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which CCB is most similar to b-blockers in effect?   show
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MOA statins?   show
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MOA niacin   show
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show binds cholesterol in the gut so they can't get to the hepatocytes  
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MOA ezetimibe   show
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MOA fibrates   show
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show fibrates niacin lovastatin  
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which cholesterol agents affect absorption of exogenous cholesterol   show
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effects of statins on: LDL HDL TGs   show
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effects of niacin on LDL HDL TGs   show
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show down a lot (not as much as statins) none slightly UP  
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show down a lot (not as much as statins) none none  
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show down a little up DOWN A FRIGGIN TON!  
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what 2 cholesterol drugs, if taken concurrently, will cause rhabdomyolysis   show
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which cholesterol drugs increase LFTs?   show
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which cholesterol drug --> GI discomfort   show
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antidote to dig toxicity   show
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show Na channel blockers B-blockers K channel blockers CCBs  
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show Quinidine Amiodarone Procainamide Disopyramide  
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which drugs are in the class Ib anti-arrhythmics?   show
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show See (C)! And Can't (EnCain) We FLEe if we PROP up PHENOMS? encainide flecainide propafenone  
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show increased AP duration increased ERP increased QT interval  
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uses for class IA anti-arrhythmics   show
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MOA for class IB anti-arrhythmics   show
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show acute ventricular arrhythmias, esp post MI  
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MOA for class IC anti-arrhythmics   show
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show VT --> FV inretractable SVT LAST resort  
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show cinchonism (HA, tinnitus, thrombocytopenia, torsades de pointes from increased QT interval)  
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toxiciyt of procainamide   show
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show local anesthetic CNS stimulation/depression CV depression  
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show pro-arrhythmic (esp post-MI) prolongs refractory period  
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receptor selectivity for epi?   show
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show a1 = a2 > b1  
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show B1=b2  
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receptor selectivity for DA   show
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receptor selectivity for dobutamine   show
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show a1 > a2  
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show b2 > b1  
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receptor selectivity for terbutaline   show
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